Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.58 |
| ▸ | CA1 | P00915 | 3/20 | 0.58 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.58 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.58 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.58 |
| ▸ | CA9 | Q16790 | 2/20 | 0.58 |
| ▸ | FAAH | O00519 | 1/20 | 0.58 |
| ▸ | ELANE | P08246 | 1/20 | 0.58 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.58 |
| ▸ | CA5A | P35218 | 1/20 | 0.58 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8577557 | 0.79 | CA2 (0.58) | CA2CA1PRSS1PRSS2PRSS3 | |
| SCHEMBL88641 | 0.78 | CA2 (0.64) | CA2CA1PRSS1PRSS2PRSS3 | |
| SCHEMBL28332352 | 0.76 | CA2 (0.61) | CA2CA1PRSS1PRSS2PRSS3 | |
| SCHEMBL57239 | 0.76 | CA2 (0.61) | CA2CA1PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL11574583 | 0.76 | CA2 (0.61) | CA2CA1PRSS1PRSS2PRSS3 | |
| SCHEMBL8789586 | 0.75 | CA2 (0.54) | CA2CA1PRSS1PRSS2PRSS3 | |
| SCHEMBL31631411 | 0.75 | PRSS1 (0.67) | CA2CA1PRSS1PRSS2PRSS3 | |
| SCHEMBL22610180 | 0.75 | CA2 (0.54) | CA2CA1PRSS1PRSS2PRSS3 | |
| SCHEMBL2337896 | 0.75 | CA2 (0.53) | CA2CA1PRSS1PRSS2PRSS3 | |
| SCHEMBL6524000 | 0.75 | KMT2A (0.48) | CA2CA1CA9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1312 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107033157-B | Bisbenzylisoquinoline derivative and application thereof in preparing medicament for treating or preventing tumor | 贵州省中国科学院天然产物化学重点实验室 | 2020-05-05 | — | — | CN | claimed |
| US-10189812-B2 | Bi-benzyl isoquinoline derivative, preparation method and use thereof in hepatopathy treatment and prevention | THE KEY LABORATORY OF CHEMISTRY FOR NATURAL PRODUC (CN) | 2019-01-29 | — | — | US | claimed |
| EP-3363788-A1 | CANNABINOID RECEPTOR MODULATORS | Arena Pharmaceuticals, Inc. (US) | 2018-08-22 | — | — | EP | claimed |
| EP-3071559-B1 | (HETERO)ARYLAMIDES FOR CONTROLLING ENDOPARASITES | ELANCO TIERGESUNDHEIT AG (CH) | 2018-01-10 | — | — | EP | claimed |
| US-9820488-B2 | Compounds for the control of endoparasites | ELANCO TIERGESUNDHEIT AG (CH) | 2017-11-21 | — | — | US | claimed |
| US-20170260161-A1 | BI-BENZYL ISOQUINOLINE DERIVATIVE, PREPARATION METHOD AND USE THEREOF IN HEPATOPATHY TREATMENT AND PREVENTION | VERSITECH LIMITED (CN) | 2017-09-14 | — | — | US | claimed |
| EP-2882733-B1 | SUBSTITUTED AZINES AS PESTICIDES | NOVARTIS TIERGESUNDHEIT AG (CH) | 2017-04-26 | — | — | EP | claimed |
| EP-2288596-B1 | ALICYCLIC CARBOXYLIC ACID DERIVATIVES OF BENZOMORPHANS AND RELATED SCAFFOLDS, MEDICAMENTS CONTAINING SUCH COMPOUNDS AND THEIR USE | BOEHRINGER INGELHEIM INT (DE) | 2016-11-30 | — | — | EP | claimed |
| EP-3071559-A1 | New Compounds | Novartis Tiergesundheit AG (CH) | 2016-09-28 | — | — | EP | claimed |
| US-20160251335-A1 | NEW COMPOUNDS | ELANCO TIERGESUNDHEIT AG (CH) | 2016-09-01 | — | — | US | claimed |
| EP-0176472-B1 | METHINE AZO COMPOUNDS | CIBA-GEIGY AG (CH) | 1990-01-24 | — | — | EP | claimed |
| US-4883866-A | DYEING PAPER | CIBA-GEIGY CORPORATION (US) | 1989-11-28 | — | — | US | claimed |
| EP-0330026-A1 | Piperidinoalkyl derivatives of carboxylic acid amides | Takeda Chemical Industries, Ltd. (JP) | 1989-08-30 | — | — | EP | claimed |
| EP-0176473-B1 | METHINE AZO COMPOUNDS | CIBA-GEIGY AG (CH) | 1989-07-19 | — | — | EP | claimed |
| US-4754021-A | DYEING PAPER, POLYACRYLONITRILE, POLYESTERS | CIBA-GEIGY CORPORATION (US) | 1988-06-28 | — | — | US | claimed |
| EP-0176474-A1 | Methine azo compounds | CIBA-GEIGY AG (CH) | 1986-04-02 | — | — | EP | claimed |
| EP-0176472-A1 | Methine azo compounds | CIBA-GEIGY AG (CH) | 1986-04-02 | — | — | EP | claimed |
| EP-0129128-A2 | 2-Pyrimidinyl-1-piperazine derivatives, process for their preparation and medicines containing them | Troponwerke GmbH & Co. KG (DE) | 1984-12-27 | — | — | EP | claimed |
| US-4309221-A | ORGANIC PIGMENTS FOR MACROMOLECULAR SUBSTANCES;GOOD FASTNESS AND HEAT RESISTANCE | BAYER AKTIENGESELLSCHAFT (DE) | 1982-01-05 | — | — | US | claimed |
| US-3950347-A | NAPHTHOLACTAM DYESTUFFS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170260161-A1 | BI-BENZYL ISOQUINOLINE DERIVATIVE, PREPARATION METHOD AND USE THEREOF IN HEPATOPATHY TREATMENT AND PREVENTION | SLC10A1, SLC10A2, CYP4B1 | CA2 1644/4885CA1 2589/4885PRSS1 1763/4885 |
| US-20160251335-A1 | NEW COMPOUNDS | DDT, ACHE, PTMS | CA2 38/4885CA1 204/4885PRSS1 950/4885 |
| US-10189812-B2 | Bi-benzyl isoquinoline derivative, preparation method and use thereof in hepatopathy treatment and prevention | SLC10A1, SLC10A2, CYP4B1 | CA2 1644/4885CA1 2589/4885PRSS1 1763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.