SCHEMBL57239

SCHEMBL57239

[O]S(=O)(=O)Cc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 6/20 0.61
CA1 P00915 4/20 0.61
PRSS1 P07477 2/20 0.61
PRSS2 P07478 2/20 0.61
PRSS3 P35030 2/20 0.61
CA9 Q16790 2/20 0.61
FAAH O00519 1/20 0.61
ELANE P08246 1/20 0.61
PRTN3 P24158 1/20 0.61
CA5A P35218 1/20 0.61
MMP1 P03956 1/20 0.54
MMP2 P08253 1/20 0.54
MMP9 P14780 1/20 0.54
MMP8 P22894 1/20 0.54
MMP13 P45452 1/20 0.54
KMT2A Q03164 2/20 0.52
HSP90AA1 P07900 1/20 0.48
F2 P00734 1/20 0.48
TSHR P16473 3/20 0.47
HPGD P15428 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL88641 0.80 CA2 (0.64) CA2CA1PRSS1PRSS2PRSS3
Hydrochloric Acid SCHEMBL11574583 0.78 CA2 (0.61) CA2CA1PRSS1PRSS2PRSS3
SCHEMBL2233216 0.76 CA2 (0.58) CA2CA1PRSS1PRSS2PRSS3
Phenylmethanesulfonic Acid SCHEMBL127384 0.76 CA2 (0.58) CA2CA1PRSS1PRSS2PRSS3
SCHEMBL92893 0.76 CA2 (0.58) CA2CA1PRSS1PRSS2PRSS3
Phenylmethanesulfonic Acid SCHEMBL1749 0.76 CA2 (0.58) CA2CA1PRSS1PRSS2PRSS3
SCHEMBL9200717 0.76 PLCG1 (0.46) CA2CA1CA9MMP1MMP2
Phenylmethylsulfonylfluoride SCHEMBL3965163 0.76 PRSS1 (1.00) CA2CA1PRSS1PRSS2PRSS3
Phenylmethylsulfonylfluoride SCHEMBL24938 0.76 PRSS1 (1.00) CA2CA1PRSS1PRSS2PRSS3
Phenylmethanesulfonic Acid SCHEMBL135008 0.76 CA2 (0.58) CA2CA1PRSS1PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1373 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10081608-B2 6-acyl-1,2,4-triazine-3,5-dione derivative and herbicides FMC CORPORATION (US) 2018-09-25 US claimed
US-20170129861-A1 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2017-05-11 US claimed
EP-3004047-B1 COMPOUNDS OF '3-(5-SUBSTITUTED OXY-2,4-DINITRO-PHENYL)-2-OXO-PROPIONIC ACID ESTER', PROCESS AND APPLICATIONS THEREOF ANTHEM BIOSCIENCES PVT LTD (IN) 2017-02-22 EP claimed
US-9573909-B2 6-acyl-1,2,4-triazine-3,5-dione derivative and herbicides FMC CORPORATION (US) 2017-02-21 US claimed
EP-2475654-B1 HERBICIDAL PYRIMIDONE DERIVATIVES DU PONT (US) 2016-12-28 EP claimed
US-20160185743-A1 15-Oxospiramilactone Derivatives, Preparation Method and Uses Thereof CENTER FOR EXCELLENCE IN MOLECULAR CELL SCIENCE, CHINESE ACADEMY OF SCIENCES (CN) 2016-06-30 US claimed
EP-3020709-A1 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES FMC CORPORATION (US) 2016-05-18 EP claimed
EP-2542538-B1 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES FMC CORP (US) 2015-12-30 EP claimed
US-20150322094-A1 USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2015-11-12 US claimed
US-20150203457-A1 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 2015-07-23 US claimed
EP-0065757-B1 1-(3-HALO-2-PYRIDINYL)PIPERAZINES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM MERCK & CO. INC. (US) 1985-01-09 EP claimed
EP-0129506-A2 Heterocyclically substituted thio(cyclo)alkane polycarboxylic acids CIBA-GEIGY AG (CH) 1984-12-27 EP claimed
EP-0061281-B1 BIS-ESTERS OF METHANEDIOL WITH ACETONIDES OF AMPICILLIN OR AMOXICILLIN AND PENICILLANIC ACID 1,1-DIOXIDE PFIZER INC. (US) 1984-11-07 EP claimed
EP-0024639-B1 ORGANIC SULFOXIDES HAVING A LATENT ALLYL GROUP, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICAL ENZYME INHIBITING COMPOSITION COMPRISING THE SAME MERCK & CO. INC. (US) 1984-06-06 EP claimed
EP-0026307-B1 ORGANIC SULFOXIDES, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICAL ENZYME INHIBITING COMPOSITIONS COMPRISING THE SAME MERCK & CO. INC. (US) 1983-11-23 EP claimed
EP-0025857-B1 ORGANIC SULFOXIDES HAVING A LATENT ALLYL GROUP, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICAL ANTIBACTERIAL COMPOSITION COMPRISING THE SAME MERCK & CO. INC. (US) 1983-07-27 EP claimed
EP-0041047-A2 Dioxide compounds, process for their preparation and their use CIBA-GEIGY AG (CH) 1981-12-02 EP claimed
EP-0008045-B1 (1,2)-ANNELLATED 7-PHENYL-1,4-BENZODIAZEPINE DERIVATIVES AND SALTS THEREOF, PROCESSES FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM Kali-Chemie Pharma GmbH (DE) 1981-09-30 EP claimed
EP-0008045-A1 (1,2)-Annellated 7-phenyl-1,4-benzodiazepine derivatives and salts thereof, processes for their preparation and medicaments containing them Kali-Chemie Pharma GmbH (DE) 1980-02-20 EP claimed
US-4011208-A 3-CYANO OR ACYL-4-ARYL-5-ARYLAZO-6-HYDROXYPYRIDONE-2 DYES SANDOZ LTD. (CH) 1977-03-08 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10081608-B2 6-acyl-1,2,4-triazine-3,5-dione derivative and herbicides DDT, AADAC, DAZAP1 CA2 1029/4885CA1 1394/4885PRSS1 4432/4885
US-20160185743-A1 15-Oxospiramilactone Derivatives, Preparation Method and Uses Thereof WNT1, WNT3, WNT3A CA2 2678/4885CA1 3083/4885PRSS1 1017/4885
US-20170129861-A1 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES DDT, AADAC, DAZAP1 CA2 1029/4885CA1 1394/4885PRSS1 4432/4885
US-20150322094-A1 USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS CAT, HSF1, HPD CA2 341/4885CA1 1091/4885PRSS1 3542/4885
US-20150203457-A1 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES DDT, AADAC, DAZAP1 CA2 1029/4885CA1 1394/4885PRSS1 4432/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.