Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HBB | P68871 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | PRKACG | P22612 | 1/20 | 0.40 |
| ▸ | PRKACB | P22694 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31285917 | 0.81 | ALDH1A1 (0.53) | ALDH1A1TSHRSMN1; SMN2ALOX15KDM4E | |
| SCHEMBL10347428 | 0.81 | ALDH1A1 (0.53) | ALDH1A1TSHRSMN1; SMN2ALOX15KDM4E | |
| SCHEMBL2027130 | 0.79 | LDHA (0.45) | ALDH1A1TSHRSMN1; SMN2HPGDPARP1 | |
| SCHEMBL6723373 | 0.78 | ALDH1A1 (0.59) | ALDH1A1TSHRSMN1; SMN2KDM4EHPGD | |
| SCHEMBL31257840 | 0.77 | TNKS2 (0.45) | ALDH1A1TSHRSMN1; SMN2ALOX15KDM4E | |
| SCHEMBL5696335 | 0.77 | ALDH1A1 (0.50) | ALDH1A1TSHRSMN1; SMN2ALOX15KDM4E | |
| SCHEMBL31257908 | 0.74 | SMN1; SMN2 (0.41) | ALDH1A1TSHRSMN1; SMN2ALOX15KDM4E | |
| SCHEMBL8431590 | 0.71 | PARP1 (0.44) | ALDH1A1KDM4EHPGDLCKPRKACA | |
| SCHEMBL3269756 | 0.70 | ALDH1A1 (0.58) | ALDH1A1TSHRSMN1; SMN2ALOX15KDM4E | |
| SCHEMBL11011279 | 0.70 | PARP1 (0.55) | ALDH1A1SMN1; SMN2KDM4EHPGDLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6673804-B1 | PREVENTING OR TREATING ARTHRITIS (PARTICULARLY OSTEOARTHRITIS) OR INHIBITING METASTASIS, INVASION OR GROWTH OF CANCER (PARTICULARLY BREAST CANCER) | SANKYO COMPANY, LIMITED (JP) | 2004-01-06 | — | — | US | disclosed |
| EP-1069110-A1 | SULFONAMIDE DERIVATIVES | Sankyo Company Limited (JP) | 2001-01-17 | — | — | EP | disclosed |