Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CTRC | Q99895 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5883114 | 0.79 | NPSR1 (0.41) | HPGDLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL5883035 | 0.78 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1SMN1; SMN2ERN1 | |
| SCHEMBL11438824 | 0.77 | LMNA (0.53) | HPGDLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL4451990 | 0.74 | LMNA (0.58) | HPGDLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL6517024 | 0.74 | TSHR (0.46) | HPGDLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL671508 | 0.74 | EGFR (0.48) | MEN1KMT2AERN1KDM4EL3MBTL1 | |
| SCHEMBL671525 | 0.74 | ALDH1A1 (0.48) | LMNAMEN1KMT2AALDH1A1ERN1 | |
| SCHEMBL2601402 | 0.74 | SMN1; SMN2 (0.61) | MEN1KMT2ASMN1; SMN2HSD17B10 | |
| SCHEMBL10617873 | 0.73 | HPGD (0.57) | HPGDLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL672287 | 0.72 | ERN1 (0.51) | HPGDLMNAKMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9422273-B2 | Compounds act at multiple prostaglandin receptors giving a general anti-inflammatory response | ALLERGAN, INC. (US) | 2016-08-23 | — | — | US | disclosed |
| US-9422273-B2 | Compounds act at multiple prostaglandin receptors giving a general anti-inflammatory response | ALLERGAN, INC. (US) | 2016-08-23 | — | — | US | disclosed |
| US-9422273-B2 | Compounds act at multiple prostaglandin receptors giving a general anti-inflammatory response | ALLERGAN, INC. (US) | 2016-08-23 | — | — | US | disclosed |
| US-20160068520-A1 | COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | ALLERGAN, INC. | 2016-03-10 | — | — | US | disclosed |
| US-20160068520-A1 | COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | ALLERGAN, INC. | 2016-03-10 | — | — | US | disclosed |
| US-20160068520-A1 | COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | ALLERGAN, INC. | 2016-03-10 | — | — | US | disclosed |
| US-9085567-B2 | Compounds act at multiple prostaglandin receptors giving a general anti-inflammatory response | ALLERGAN, INC. (US) | 2015-07-21 | — | — | US | disclosed |
| US-9085567-B2 | Compounds act at multiple prostaglandin receptors giving a general anti-inflammatory response | ALLERGAN, INC. (US) | 2015-07-21 | — | — | US | disclosed |
| US-9085567-B2 | Compounds act at multiple prostaglandin receptors giving a general anti-inflammatory response | ALLERGAN, INC. (US) | 2015-07-21 | — | — | US | disclosed |
| US-20140249192-A1 | COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | ALLERGAN, INC. (US) | 2014-09-04 | — | — | US | disclosed |
| US-20130150417-A1 | COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | ALLERGAN, INC. (US) | 2013-06-13 | — | — | US | disclosed |
| WO-2012145737-A1 | FATTY ACID AMIDE HYDROLASE INHIBITORS FOR TREATING | ALLERGAN, INC. (US) | 2012-10-26 | — | — | WO | disclosed |
| US-20120270915-A1 | FATTY ACID AMIDE HYDROLASE INHIHIBITORS FOR TREATING PAIN | ENERGY, UNITED STATES DEPARTMENT OF | 2012-10-25 | — | — | US | disclosed |
| US-20120270915-A1 | FATTY ACID AMIDE HYDROLASE INHIHIBITORS FOR TREATING PAIN | ENERGY, UNITED STATES DEPARTMENT OF | 2012-10-25 | — | — | US | disclosed |
| US-20120270915-A1 | FATTY ACID AMIDE HYDROLASE INHIHIBITORS FOR TREATING PAIN | ENERGY, UNITED STATES DEPARTMENT OF | 2012-10-25 | — | — | US | disclosed |
| US-20120077858-A1 | COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | ALLERGAN, INC. (US) | 2012-03-29 | — | — | US | disclosed |
| US-20120077858-A1 | COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | ALLERGAN, INC. (US) | 2012-03-29 | — | — | US | disclosed |
| US-20120077858-A1 | COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | ALLERGAN, INC. (US) | 2012-03-29 | — | — | US | disclosed |
| WO-2012024559-A1 | COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | ALLERGAN, INC. (US) | 2012-02-23 | — | — | WO | disclosed |
| WO-2012024559-A1 | COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | ALLERGAN, INC. (US) | 2012-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077858-A1 | COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | PTGER1, PTGER4, PTGER3 | HPGD 484/4885LMNA 4416/4885MEN1 4846/4885 |
| US-20120270915-A1 | FATTY ACID AMIDE HYDROLASE INHIHIBITORS FOR TREATING PAIN | FAAH, FAAH2, FAH | HPGD 86/4885LMNA 2858/4885MEN1 3949/4885 |
| US-20130150417-A1 | COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | PTGER1, PTGER4, PTGER3 | HPGD 508/4885LMNA 4321/4885MEN1 4795/4885 |
| US-20160068520-A1 | COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | PTGER1, PTGER4, PTGER3 | HPGD 484/4885LMNA 4416/4885MEN1 4846/4885 |
| US-20140249192-A1 | COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | PTGER1, PTGER4, PTGER3 | HPGD 484/4885LMNA 4416/4885MEN1 4846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.