Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | BCR | P11274 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL673173 | 0.92 | ALDH1A1 (0.48) | APPALDH1A1GRM5L3MBTL1TDP1 | |
| SCHEMBL714294 | 0.86 | APP (0.59) | APPALDH1A1GRM5CA12CA1 | |
| SCHEMBL673162 | 0.84 | APP (0.55) | APPALDH1A1GRM5CA12CA1 | |
| SCHEMBL673820 | 0.82 | APP (0.69) | APPALDH1A1CA12CA1CA2 | |
| SCHEMBL674040 | 0.79 | ALDH1A1 (0.65) | APPALDH1A1GRM5CA12CA1 | |
| SCHEMBL1306505 | 0.79 | APP (0.41) | APPALDH1A1GRM5CYP1A2 | |
| SCHEMBL1005880 | 0.79 | APP (0.77) | APPALDH1A1ABL1ABCB1BCR | |
| SCHEMBL852844 | 0.78 | GRM5 (0.59) | GRM5CA12CA1CA2CA9 | |
| SCHEMBL712263 | 0.77 | APP (0.52) | APPALDH1A1GRM5CA12CA1 | |
| SCHEMBL1306384 | 0.77 | GABRA1 (0.38) | APPALDH1A1GRM5CYP1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8703388-B2 | Optical data storage media | GENERAL ELECTRIC COMPANY (US) | 2014-04-22 | — | — | US | disclosed |
| EP-2290408-B1 | Compositions, optical data storage media and methods for using the optical data storage media | GEN ELECTRIC (US) | 2012-08-15 | — | — | EP | disclosed |
| US-20120163145-A1 | OPTICAL DATA STORAGE MEDIA | GENERAL ELECTRIC COMPANY (US) | 2012-06-28 | — | — | US | disclosed |
| US-8124299-B2 | Methods for using optical data storage media | GENERAL ELECTRIC COMPANY (US) | 2012-02-28 | — | — | US | disclosed |
| US-20110053054-A1 | COMPOSITIONS, OPTICAL DATA STORAGE MEDIA AND METHODS FOR USING THE OPTICAL DATA STORAGE MEDIA | GENERAL ELECTRIC COMPANY (US) | 2011-03-03 | — | — | US | disclosed |
| EP-2290408-A1 | Compositions, optical data storage media and methods for using the optical data storage media | General Electric Company (US) | 2011-03-02 | — | — | EP | disclosed |