SCHEMBL6732196

SCHEMBL6732196

CC(C)(C)NS(=O)(=O)c1ccccc1C(F)(F)F

nearest known ligand 0.57

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC22A12 Q96S37 15/20 0.57
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
ALDH1A1 P00352 1/20 0.51
CYP2C9 P11712 2/20 0.50
SLC22A6 Q4U2R8 2/20 0.50
SLC22A8 Q8TCC7 2/20 0.50
SLC22A11 Q9NSA0 2/20 0.50
KAT6A Q92794 1/20 0.49
RXFP1 Q9HBX9 1/20 0.49
CYP3A4 P08684 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4029025 0.83 SLC22A12 (0.58) SLC22A12MEN1KMT2AALDH1A1CYP2C9
SCHEMBL2803354 0.82 NSD2 (0.58) MEN1KMT2AALDH1A1CYP2C9CYP3A4
SCHEMBL14676717 0.82 MEN1 (0.56) SLC22A12MEN1KMT2AALDH1A1CYP2C9
SCHEMBL17698979 0.81 SLC22A12 (0.60) SLC22A12MEN1KMT2AALDH1A1CYP2C9
SCHEMBL422146 0.79 SLC22A12 (0.58) SLC22A12MEN1KMT2AALDH1A1CYP2C9
SCHEMBL1767681 0.79 SLC22A12 (0.58) SLC22A12MEN1KMT2AALDH1A1CYP2C9
SCHEMBL29536289 0.79 SLC22A12 (0.58) SLC22A12MEN1KMT2AALDH1A1CYP2C9
SCHEMBL14675594 0.79 MEN1 (0.50) SLC22A12MEN1KMT2AALDH1A1CYP2C9
SCHEMBL15726861 0.77 ALDH1A1 (0.47) SLC22A12MEN1KMT2AALDH1A1CYP2C9
SCHEMBL27529773 0.77 CA12 (0.57) SLC22A12MEN1KMT2ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110015185-A1 Benzofuran Compounds BIOVITRUM AB (SE) 2011-01-20 US disclosed
US-7820675-B2 Benzofuran compounds BIOVITRUM AB (SE) 2010-10-26 US disclosed
US-7820675-B2 Benzofuran compounds BIOVITRUM AB (SE) 2010-10-26 US disclosed
US-6677277-B1 Substituted sulphonyl amino(thio)carbonyl compounds and their use as herbicides BAYER AKTIENGESELLSCHAFT (DE) 2004-01-13 US disclosed
EP-0906293-B1 SUBSTITUTED SULPHONYL AMINO(THIO)CARBONYL COMPOUNDS AND THEIR USE AS HERBICIDES BAYER CROPSCIENCE AG (DE) 2003-09-17 EP disclosed
EP-0906293-A1 SUBSTITUTED SULPHONYL AMINO(THIO)CARBONYL COMPOUNDS AND THEIR USE AS HERBICIDES BAYER AG (DE) 1999-04-07 EP disclosed
WO-1997046540-A1 SUBSTITUTED SULPHONYL AMINO(THIO)CARBONYL COMPOUNDS AND THEIR USE AS HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-12-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110015185-A1 Benzofuran Compounds HTR6, HTR1F, HTR1A SLC22A12 1469/4885MEN1 2814/4885KMT2A 3354/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.