Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24054967 | 0.86 | GRM2 (0.40) | ALDH1A1NPSR1TSHRMAPK1KDM4E | |
| SCHEMBL30198157 | 0.86 | GRM2 (0.40) | ALDH1A1NPSR1TSHRMAPK1KDM4E | |
| SCHEMBL6738553 | 0.85 | ELANE (0.44) | ALDH1A1NPSR1TSHRMAPK1LMNA | |
| SCHEMBL1522411 | 0.84 | ALDH1A1 (0.40) | ALDH1A1NPSR1TSHRMAPK1KDM4E | |
| SCHEMBL5304933 | 0.84 | ALDH1A1 (0.40) | ALDH1A1NPSR1TSHRMAPK1LMNA | |
| SCHEMBL15966769 | 0.81 | ALDH1A1 (0.38) | ALDH1A1NPSR1TSHRMAPK1LMNA | |
| SCHEMBL6685071 | 0.78 | TSHR (0.35) | ALDH1A1NPSR1TSHRMAPK1KDM4E | |
| SCHEMBL5308775 | 0.77 | ALDH1A1 (0.55) | ALDH1A1NPSR1TSHRMAPK1LMNA | |
| SCHEMBL15966770 | 0.76 | JAK2 (0.46) | ALDH1A1LMNAKDM4EGRM2ELANE | |
| SCHEMBL6234062 | 0.73 | DNM1 (0.40) | ALDH1A1NPSR1LMNASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040147739-A1 | Novel anti-infectives | SMITHKLINE BEECHAM CORPORATION | 2004-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147739-A1 | Novel anti-infectives | RPL5, RPL7, RPL35 | ALDH1A1 1494/4885NPSR1 3358/4885TSHR 4433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.