SCHEMBL6734384

SCHEMBL6734384

COCc1c(N)cccc1Cl

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.47
TSHR P16473 2/20 0.43
TAAR1 Q96RJ0 2/20 0.42
NR4A2 P43354 1/20 0.42
CYP3A4 P08684 1/20 0.39
PIK3CA P42336 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
IDO1 P14902 3/20 0.37
DPP4 P27487 1/20 0.37
GAA P10253 1/20 0.37
CYP2D6 P10635 1/20 0.36
CYP2C19 P33261 1/20 0.36
ADRA1A P35348 1/20 0.36
BCHE P06276 1/20 0.35
ACHE P22303 1/20 0.35
AKR1B1 P15121 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4796836 0.85 SMN1; SMN2 (0.48) ALDH1A1TAAR1SMN1; SMN2IDO1DPP4
SCHEMBL5188519 0.85 CYP3A4 (0.42) ALDH1A1TSHRCYP3A4PIK3CASMN1; SMN2
SCHEMBL18185003 0.81 KDM4E (0.46) ALDH1A1TSHRTAAR1NR4A2CYP3A4
SCHEMBL19654351 0.80 TSHR (0.43) ALDH1A1TSHRTAAR1NR4A2CYP3A4
SCHEMBL18184977 0.79 ALDH1A1 (0.42) ALDH1A1TSHRTAAR1NR4A2CYP3A4
SCHEMBL18185048 0.79 ALDH1A1 (0.42) ALDH1A1TSHRTAAR1NR4A2CYP3A4
SCHEMBL18184947 0.78 ALDH1A1 (0.41) ALDH1A1TSHRTAAR1NR4A2CYP3A4
SCHEMBL12016024 0.78 SMN1; SMN2 (0.39) TAAR1SMN1; SMN2GAAAKR1B1
SCHEMBL15352694 0.78 CD44 (0.46) ALDH1A1TSHRCYP3A4PIK3CADPP4
SCHEMBL21027998 0.78 SMN1; SMN2 (0.39) ALDH1A1TAAR1SMN1; SMN2IDO1DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3088382-B1 METHOD FOR PRODUCING NITRO COMPOUND SUMITOMO CHEMICAL CO (JP) 2018-07-11 EP disclosed
US-9561998-B2 Method for producing nitro compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-02-07 US disclosed
US-20160318846-A1 METHOD FOR PRODUCING NITRO COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-11-03 US disclosed
EP-3088382-A1 METHOD FOR PRODUCING NITRO COMPOUND Sumitomo Chemical Company Limited (JP) 2016-11-02 EP disclosed
US-6683213-B1 CHEMICAL INTERMEDIATES FOR PYRIDINEDICARBOXAMIDE HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 2004-01-27 US disclosed
EP-1165496-B1 SUBSTITUTED ANILINE COMPOUNDS BASF AG (DE) 2003-07-09 EP disclosed
US-6472349-B1 Pyridine-2,3-dicarboxylic acid diamides BASF AKTIENGESELLSCHAFT (DE) 2002-10-29 US disclosed
EP-1165515-A1 PYRIDINE-2,3-DICARBOXYLIC ACID DIAMIDES BASF AKTIENGESELLSCHAFT (DE) 2002-01-02 EP disclosed
EP-1165496-A1 SUBSTITUTED ANILINE COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2002-01-02 EP disclosed
WO-2000059868-A1 SUBSTITUTED ANILINE COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2000-10-12 WO disclosed
WO-2000058288-A1 PYRIDINE-2,3-DICARBOXYLIC ACID DIAMIDES BASF AKTIENGESELLSCHAFT (DE) 2000-10-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160318846-A1 METHOD FOR PRODUCING NITRO COMPOUND NOS1, NOS3, NOS2 ALDH1A1 2305/4885TSHR 1679/4885TAAR1 565/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.