Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.47 |
| ▸ | FPR2 | P25090 | 3/20 | 0.47 |
| ▸ | FPR3 | P25089 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29933653 | 0.84 | USP30 (0.59) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL28834165 | 0.84 | USP30 (0.59) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL28834164 | 0.84 | USP30 (0.59) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL69769 | 0.84 | ALDH1A1 (0.58) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL2873727 | 0.81 | ALDH1A1 (0.75) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL2606333 | 0.80 | ALDH1A1 (0.59) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL70137 | 0.80 | ALDH1A1 (0.59) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL12069062 | 0.80 | ALDH1A1 (0.59) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL6249997 | 0.80 | ALDH1A1 (0.56) | ALDH1A1NPC1MAPTMAPK1HTT | |
| SCHEMBL70179 | 0.79 | ALDH1A1 (0.58) | ALDH1A1NPC1MAPTMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142920-A1 | Bipiperidinyl-derivatives and their use as chemokine receptors inhibitors | NOVARTIS | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142920-A1 | Bipiperidinyl-derivatives and their use as chemokine receptors inhibitors | CCR5, CCR2, CXCR3 | ALDH1A1 1912/4885NPC1 921/4885MAPT 4123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.