SCHEMBL6735345

SCHEMBL6735345

Nc1c(S(=O)(=O)c2ccc(Oc3ccccc3)c(O)c2N)ccc(Oc2ccccc2)c1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 1/20 0.44
TTR P02766 3/20 0.41
CTNNB1 P35222 1/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
ALB P02768 1/20 0.39
THRB P10828 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
POLB P06746 1/20 0.39
APEX1 P27695 1/20 0.39
RXFP1 Q9HBX9 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
SOS1 Q07889 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21796066 0.85 ADORA2A (0.51) ADORA2ATTRCTNNB1MEN1KMT2A
SCHEMBL6741084 0.81 ADORA2A (0.42) ADORA2ATTRCTNNB1MEN1KMT2A
SCHEMBL690190 0.78 ADORA2A (0.47) ADORA2ATTRCTNNB1MEN1KMT2A
SCHEMBL711860 0.78 CASP1 (0.44) TTRCTNNB1KMT2APOLBACLY
SCHEMBL8852898 0.78 CYP1A2 (0.49) ADORA2ATTRCTNNB1MEN1KMT2A
SCHEMBL11297225 0.76 ACLY (0.40) ADORA2ATTRCTNNB1MEN1KMT2A
SCHEMBL7764006 0.75 ADORA2A (0.49) ADORA2ATTRCTNNB1MEN1KMT2A
SCHEMBL15051973 0.75 SOS1 (0.51) ADORA2ATTRMEN1KMT2AALB
SCHEMBL6735347 0.74 CA1 (0.41) TTRMEN1KMT2ATDP1POLB
SCHEMBL9768120 0.74 LTA4H (0.55) TTRCTNNB1KMT2ACYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6686106-B2 POLYIMIDESILOXANE COPOLYMERS UBE INDUSTRIES, LTD. (JP) 2004-02-03 US disclosed
US-20020001763-A1 Photosensitive resin compositions, insulating films, and processes for formation of the films UBE INDUSTRIES, LTD. 2002-01-03 US disclosed
US-5643986-A STORAGE STABLE, PROTECTIVE FILMS UBE INDUSTRIES, LTD. (JP) 1997-07-01 US disclosed