Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | HRH2 | P25021 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 4/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.39 |
| ▸ | HTR3B | O95264 | 2/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | CD44 | P16070 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6660307 | 0.82 | HTR3A (0.32) | HRH4HRH3HRH2HRH1TDP1 | |
| SCHEMBL6736198 | 0.69 | GABRR1 (0.33) | GABRR1HTR3A | |
| SCHEMBL11336370 | 0.69 | GABRR1 (0.47) | HRH4HRH3HRH2HRH1TDP1 | |
| SCHEMBL8659893 | 0.66 | TRPA1 (0.37) | TDP1SMN1; SMN2 | |
| SCHEMBL6569238 | 0.66 | — | — | |
| SCHEMBL6658784 | 0.66 | HRH3 (0.56) | HRH4HRH3HRH2HRH1TDP1 | |
| SCHEMBL7404052 | 0.66 | CYP17A1 (0.31) | — | |
| SCHEMBL11102609 | 0.65 | HTR3A (0.54) | HRH4HRH3HRH2HRH1TDP1 | |
| SCHEMBL10743073 | 0.65 | HRH2 (0.53) | HRH4HRH3HRH2HRH1TDP1 | |
| SCHEMBL8086291 | 0.65 | KIF11 (0.34) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040127718-A1 | Substituted imidazoles | NOVO NORDISK A/S (DK) | 2004-07-01 | — | — | US | disclosed |
| US-20030181479-A1 | Substituted imidazoles | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2003-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030181479-A1 | Substituted imidazoles | HRH3, HRH4, HRH2 | HRH4 2/4885HRH3 1/4885HRH2 3/4885 |
| US-20040127718-A1 | Substituted imidazoles | HRH3, HRH4, HRH2 | HRH4 2/4885HRH3 1/4885HRH2 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.