Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10109424 | 0.81 | TDP1 (0.64) | TDP1MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL20832256 | 0.80 | TDP1 (0.48) | TDP1MEN1KMT2AALDH1A1CYP3A4 | |
| Fospirate SCHEMBL30538657 | 0.78 | TDP1 (0.65) | TDP1MEN1KMT2AALDH1A1CYP3A4 | |
| Fospirate SCHEMBL6736860 | 0.78 | TDP1 (0.65) | TDP1MEN1KMT2AALDH1A1CYP3A4 | |
| Fospirate SCHEMBL117867 | 0.78 | TDP1 (0.65) | TDP1MEN1KMT2AALDH1A1CYP3A4 | |
| Chlorphrifos Oxon SCHEMBL30674408 | 0.74 | TDP1 (0.68) | TDP1MEN1KMT2AALDH1A1CYP3A4 | |
| Chlorphrifos Oxon SCHEMBL1168184 | 0.74 | TDP1 (0.68) | TDP1MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL16506502 | 0.74 | TDP1 (0.54) | TDP1MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL990015 | 0.71 | TDP1 (0.51) | TDP1MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL20835090 | 0.70 | TDP1 (0.38) | TDP1MEN1KMT2AALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110275583-A1 | Synergistic active compound combinations | BAYER CROPSCIENCE AG (DE) | 2011-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275583-A1 | Synergistic active compound combinations | ACHE, ACAT2, ACAT1 | TDP1 4212/4885MEN1 4010/4885KMT2A 3689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.