Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 11/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 11/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 9/20 | 0.40 |
| ▸ | IDE | P14735 | 1/20 | 0.39 |
| ▸ | WNT3A | P56704 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6729147 | 0.92 | MEN1 (0.42) | HPGDSMN1; SMN2NPSR1HSD17B10MEN1 | |
| SCHEMBL6729747 | 0.88 | TLR8 (0.41) | HPGDSMN1; SMN2NPSR1HSD17B10MEN1 | |
| SCHEMBL6726229 | 0.88 | TLR8 (0.41) | HPGDSMN1; SMN2NPSR1HSD17B10MEN1 | |
| SCHEMBL6736204 | 0.86 | TLR8 (0.39) | HPGDSMN1; SMN2NPSR1HSD17B10MEN1 | |
| SCHEMBL6737727 | 0.85 | TLR7 (0.48) | SMN1; SMN2MEN1KMT2ATLR8TLR7 | |
| SCHEMBL6735109 | 0.78 | ALDH1A1 (0.37) | HPGDSMN1; SMN2NPSR1HSD17B10MEN1 | |
| SCHEMBL6731903 | 0.76 | TLR8 (0.49) | SMN1; SMN2MEN1KMT2ATLR8TLR7 | |
| SCHEMBL6726461 | 0.72 | TLR7 (0.49) | HPGDSMN1; SMN2MEN1KMT2ATLR8 | |
| SCHEMBL6736462 | 0.72 | WNT3A (0.38) | IDEWNT3A | |
| SCHEMBL6731135 | 0.71 | TLR9 (0.48) | SMN1; SMN2MEN1KMT2ATLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6747023-B1 | INHIBITORS FOR ACTIVATED COAGULATION FACTOR X, COAGULATION SUPPRESSORS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-06-08 | — | — | US | disclosed |
| US-20040082611-A1 | Anticoagulants; brain disorders; respiratory system disorders; side effect reduction | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-04-29 | — | — | US | disclosed |
| EP-1104754-A1 | NOVEL SULFONYL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2001-06-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082611-A1 | Anticoagulants; brain disorders; respiratory system disorders; side effect reduction | F2, CYC1, SULT2A1 | HPGD 1172/4885SMN1; SMN2 1510/4885NPSR1 1152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.