Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | ACLY | P53396 | 3/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.35 |
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | CPT2 | P23786 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8741818 | 0.93 | ALDH1A1 (0.39) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL16393918 | 0.91 | ALDH1A1 (0.37) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL304602 | 0.85 | MGAM (0.43) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL1989298 | 0.84 | ALDH1A1 (0.39) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL10410369 | 0.82 | TSHR (0.41) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL27076088 | 0.82 | ALDH1A1 (0.37) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL28452924 | 0.82 | ALDH1A1 (0.37) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL9418856 | 0.80 | TSHR (0.38) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL11245866 | 0.80 | ALDH1A1 (0.36) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| Succinic Acid SCHEMBL8002651 | 0.80 | EGLN1 (0.39) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101657209-B | Composition for preventing and treating periodontitis comprising extract of rehmanniae radix preparata, notoginseng radix or mixture thereof as effective ingredient | OSCOTEC INC | 2014-01-01 | — | — | CN | disclosed |
| US-8333998-B2 | enhances the expression of osteoprotegerin (OPG) in osteoblasts and effectively inhibits the generation and activation of osteoclasts | OSCOTEC INC. (KR) | 2012-12-18 | — | — | US | disclosed |
| CN-101119737-B | A herbal mixture extract of pleurotus eryngii, acanthopanacis cortex and notoginseng radix and a composition comprising the same for prevention and treatment of periodontitis | OSCOTEC INC | 2012-11-28 | — | — | CN | disclosed |
| US-8227456-B2 | Pharmaceutical composition for preventing and treating metabolic bone diseases containing alpha-arylmethoxyacrylate derivatives | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2012-07-24 | — | — | US | disclosed |
| EP-1784173-B1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING METABOLIC BONE DISEASES CONTAINING ALPHA-ARYLMETHOXYACRYLATE DERIVATIVES | KOREA RES INST CHEM TECH (KR) | 2012-01-18 | — | — | EP | disclosed |
| US-8053001-B2 | enhances the expression of osteoprotegerin (OPG) in osteoblasts and effectively inhibits the generation and activation of osteoclasts | OSCOTEC INC. (KR) | 2011-11-08 | — | — | US | disclosed |
| CN-101128210-B | A herbal mixture extract of rehmanniae radix preparata and acanthopanacis cortex and a composition comprising the same for prevention and treatment of osteoporosis | OSCOTEC INC | 2011-09-07 | — | — | CN | disclosed |
| US-7879835-B2 | treating osteoporosis, comprising administering drugs such as (E)-methyl 2-(2-((4-octylphenoxy)methyl)-3-methoxyacrylate, which inhibit osteoclast formation or resorption activity; side effect reduction | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2011-02-01 | — | — | US | disclosed |
| US-20100256367-A1 | Pharmaceutical Composition For Preventing and Treating Metabolic Bone Diseases Containing Alpha-Arylmethoxyactylate Derivatives | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2010-10-07 | — | — | US | disclosed |
| US-7794760-B2 | Herbal mixture extract of Pleurotus eryngii, Acanthopanacis Cortex and Notoginseng Radix and a composition comprising the same for prevention and treatment of periodontitis | OSCOTEC INC. (KR) | 2010-09-14 | — | — | US | disclosed |
| EP-1848450-A1 | A HERBAL MIXTURE EXTRACT OF PLEUROTUS ERYNGII, ACANTHOPANACIS CORTEX AND NOTOGINSENG RADIX AND A COMPOSITION COMPRISING THE SAME FOR PREVENTION AND TREATMENT OF PERIODONTITIS | Oscotec Inc. (KR) | 2007-10-31 | — | — | EP | disclosed |
| EP-1784173-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING METABOLIC BONE DISEASES CONTAINING ALPHA-ARYLMETHOXYACRYLATE DERIVATIVES | Korea Research Institute of Chemical Technology (KR) | 2007-05-16 | — | — | EP | disclosed |
| WO-2006091030-A1 | A HERBAL MIXTURE EXTRACT OF REHMANNIAE RADIX PREPARATA AND ACANTHOPANACIS CORTEX AND A COMPOSITION COMPRISING THE SAME FOR PREVENTION AND TREATMENT OF OSTEOPOROSIS | OSCOTEC INC. (KR) | 2006-08-31 | — | — | WO | disclosed |
| WO-2006088324-A1 | A HERBAL MIXTURE EXTRACT OF PLEUROTUS ERYNGII, ACANTHOPANACIS CORTEX AND NOTOGINSENG RADIX AND A COMPOSITION COMPRISING THE SAME FOR PREVENTION AND TREATMENT OF PERIODONTITIS | OSCOTEC INC. (KR) | 2006-08-24 | — | — | WO | disclosed |
| US-20060004088-A1 | Furan derivatives for preventing and curing osteoporosis and pharmaceutical compositions containing the same | OCT INC. (KR) | 2006-01-05 | — | — | US | disclosed |
| WO-2005123054-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING METABOLIC BONE DISEASES CONTAINING ALPHA-ARYLMETHOXYACRYLATE DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2005-12-29 | — | — | WO | disclosed |
| WO-2004037804-A1 | FURAN DERIVATIVES FOR PREVENTING AND CURING OSTEOPOROSIS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | OSCOTEC INC. (KR) | 2004-05-06 | — | — | WO | disclosed |
| EP-0785800-A1 | PROBIOTIC FOR CONTROL OF $i(SALMONELLA) | THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Agriculture (US) | 1997-07-30 | — | — | EP | disclosed |
| EP-0785800-A4 | — | US AGRICULTURE (US) | 1997-07-30 | — | — | EP | disclosed |
| WO-1995016461-A1 | PROBIOTIC FOR CONTROL OF $i(SALMONELLA) | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1995-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256367-A1 | Pharmaceutical Composition For Preventing and Treating Metabolic Bone Diseases Containing Alpha-Arylmethoxyactylate Derivatives | ARSA, BMP2, BMP1 | ALDH1A1 721/4885TSHR 3993/4885CYP2D6 1376/4885 |
| US-20060004088-A1 | Furan derivatives for preventing and curing osteoporosis and pharmaceutical compositions containing the same | SOST, PTH1R, PTMS | ALDH1A1 784/4885TSHR 4252/4885CYP2D6 2138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.