Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.46 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1751871 | 1.00 | HSD11B1 (0.62) | HSD11B1KMT2AMEN1NPC1HSP90AA1 | |
| SCHEMBL297691 | 1.00 | HSD11B1 (0.62) | HSD11B1KMT2AMEN1NPC1HSP90AA1 | |
| SCHEMBL31613215 | 1.00 | HSD11B1 (0.62) | HSD11B1KMT2AMEN1NPC1HSP90AA1 | |
| SCHEMBL3328957 | 0.89 | HSD11B1 (0.54) | HSD11B1KMT2AMEN1NPC1HSP90AA1 | |
| SCHEMBL3328961 | 0.89 | HSD11B1 (0.54) | HSD11B1KMT2AMEN1NPC1HSP90AA1 | |
| SCHEMBL14752283 | 0.89 | HSD11B1 (0.54) | HSD11B1KMT2AMEN1NPC1HSP90AA1 | |
| SCHEMBL38650618 | 0.88 | HSD11B1 (0.58) | HSD11B1KMT2AMEN1NPC1HSP90AA1 | |
| SCHEMBL1812179 | 0.88 | HSD11B1 (0.58) | HSD11B1KMT2AMEN1NPC1HSP90AA1 | |
| SCHEMBL30364986 | 0.87 | NFE2L2 (0.56) | HSD11B1KMT2AMEN1NPC1NFE2L2 | |
| SCHEMBL14703725 | 0.87 | NFE2L2 (0.56) | HSD11B1KMT2AMEN1NPC1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180053893-A1 | CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2018-02-22 | — | — | US | disclosed |
| US-20130059996-A1 | Boron-Containing PI-Electron Materials Incorporating Formally Aromatic and Neutral Borepin Rings | THE JOHNS HOPKINS UNIVERSITY | 2013-03-07 | — | — | US | disclosed |
| US-20130059996-A1 | Boron-Containing PI-Electron Materials Incorporating Formally Aromatic and Neutral Borepin Rings | THE JOHNS HOPKINS UNIVERSITY | 2013-03-07 | — | — | US | disclosed |
| EP-0663391-B1 | Sulphuric acid esters of sugar alcohols for the treatment of arteriosclerotic changes in the vascular walls | HOFFMANN LA ROCHE (CH) | 1997-04-09 | — | — | EP | disclosed |
| US-5521160-A | COMPOUNDS FOR TREATMENT OF ATHERIOSCLEROSIS IN BLOOD VESSELS AND PREVENTION OF RESTENOSIS AFTER ANGIOPLASTY | HOFFMANN-LA ROCHE INC. (US) | 1996-05-28 | — | — | US | disclosed |
| EP-0663391-A1 | Sulphuric acid esters of sugar alcohols for the treatment of arteriosclerotic changes in the vascular walls | F. HOFFMANN-LA ROCHE AG (CH) | 1995-07-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180053893-A1 | CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | CRY1, CRY2, CCNE2 | HSD11B1 1220/4885KMT2A 1836/4885MEN1 450/4885 |
| US-20130059996-A1 | Boron-Containing PI-Electron Materials Incorporating Formally Aromatic and Neutral Borepin Rings | PNN, CIAPIN1, VNN1 | HSD11B1 3340/4885KMT2A 4092/4885MEN1 2375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.