Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 9/20 | 0.55 |
| ▸ | CTSB | P07858 | 8/20 | 0.55 |
| ▸ | CTSL | P07711 | 4/20 | 0.53 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.52 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 3/20 | 0.47 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6738509 | 1.00 | CTSS (0.55) | CTSSCTSBCTSLTAS1R3TAS1R1 | |
| SCHEMBL6744256 | 0.83 | CTSL (0.72) | CTSSCTSBCTSLALDH1A1CTSK | |
| SCHEMBL6744264 | 0.83 | CTSL (0.72) | CTSSCTSBCTSLALDH1A1CTSK | |
| SCHEMBL6738426 | 0.82 | CTSS (0.77) | CTSSCTSBCTSLCTSK | |
| SCHEMBL6738423 | 0.82 | CTSS (0.77) | CTSSCTSBCTSLCTSK | |
| SCHEMBL6742242 | 0.82 | CTSB (0.64) | CTSSCTSBCTSLCTSK | |
| SCHEMBL6742241 | 0.82 | CTSB (0.64) | CTSSCTSBCTSLCTSK | |
| SCHEMBL5528180 | 0.81 | MEN1 (0.53) | CTSSCTSBCTSLTAS1R3TAS1R1 | |
| SCHEMBL5528176 | 0.81 | MEN1 (0.53) | CTSSCTSBCTSLTAS1R3TAS1R1 | |
| SCHEMBL6738512 | 0.81 | SMN1; SMN2 (0.54) | TAS1R3TAS1R1MEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040014796-A1 | Novel compounds and compositions as cathepsin S inhititors | AXYS PHARMACEUTICALS, INC. | 2004-01-22 | — | — | US | disclosed |
| US-6492362-B1 | Compounds and compositions as cathepsin S inhibitors | AXYS PHARMACEUTICALS, INC. | 2002-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040014796-A1 | Novel compounds and compositions as cathepsin S inhititors | CTSS, CTSB, CTSE | CTSS 1/4885CTSB 2/4885CTSL 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.