SCHEMBL6738571

SCHEMBL6738571

O=C(CCCBr)OC(=O)CC/C(=N/O)OC(=O)CCCBr

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL781568 0.86 ALDH1A1 (0.34) ALDH1A1
SCHEMBL5069484 0.82 LMNA (0.42) ALDH1A1
SCHEMBL1247297 0.82 TSHR (0.45) ALDH1A1
SCHEMBL15009749 0.81 TSHR (0.44) ALDH1A1
SCHEMBL14432755 0.81 DGKA (0.46) ALDH1A1
SCHEMBL3173473 0.80 ALDH1A1 (0.48) ALDH1A1
SCHEMBL17204502 0.79 DGKA (0.48) ALDH1A1
SCHEMBL7262371 0.79 DGKA (0.48) ALDH1A1
SCHEMBL7887094 0.79 DGKA (0.48) ALDH1A1
SCHEMBL5968591 0.79 EGLN1 (0.39) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE38416-E1 NUCLEOTIDE BASES COMPRISING PYRAZOLO(3,4-D)PYRIMIDINES USED FOR MEDICAL DIAGNOSIS, THERAPY, HYBRIDIZATION, ANTISENSE AGENTS OR REPORTER MOLECULES EPOCH BIOSCIENCES, INC. 2004-02-03 US disclosed
US-5824796-A MEDICAL DIAGNOSIS WITH TARGET DNA OR RNA FOR ENZYME INHIBITORS EPOCH PHARMACEUTICALS, INC. (US) 1998-10-20 US disclosed
EP-0661979-A4 CROSS-LINKING OLIGONUCLEOTIDES FOR ENZYME-MEDIATED TRIPLE STRAND FORMATION. MICROPROBE CORP (US) 1995-09-13 EP disclosed
EP-0661979-A1 CROSS-LINKING OLIGONUCLEOTIDES FOR ENZYME-MEDIATED TRIPLE STRAND FORMATION MICROPROBE CORPORATION (US) 1995-07-12 EP disclosed
WO-1993003736-A1 CROSS-LINKING OLIGONUCLEOTIDES FOR ENZYME-MEDIATED TRIPLE STRAND FORMATION MICROPROBE CORPORATION (US) 1993-03-04 WO disclosed
EP-0472648-A4 CROSSLINKING OLIGONUCLEOTIDES 1992-09-16 EP disclosed
EP-0472648-A1 CROSSLINKING OLIGONUCLEOTIDES MICROPROBE CORPORATION (US) 1992-03-04 EP disclosed
WO-1990014353-A1 CROSSLINKING OLIGONUCLEOTIDES MICROPROBE CORPORATION (US) 1990-11-29 WO disclosed