Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of D-Glutamate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | GRM8 | O00222 | 1/20 | 0.62 |
| ▸ | GRM6 | O15303 | 1/20 | 0.62 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.62 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.62 |
| ▸ | GSR | P00390 | 1/20 | 0.62 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.62 |
| ▸ | GRM5 | P41594 | 1/20 | 0.62 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.62 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.62 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.62 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.62 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.62 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.62 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.62 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.62 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.62 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.62 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.62 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| D-Glutamate SCHEMBL16336 | 0.95 | CYP1A2 (0.62) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL1782280 | 0.95 | CYP1A2 (0.62) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL218574 | 0.95 | CYP1A2 (0.62) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL11884703 | 0.95 | CYP1A2 (0.62) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL1532402 | 0.95 | CYP1A2 (0.62) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL8746869 | 0.95 | CYP1A2 (0.62) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL1899059 | 0.95 | CYP1A2 (0.62) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL718336 | 0.95 | CYP1A2 (0.62) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL5184074 | 0.95 | GRM8 (0.62) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL3747276 | 0.95 | CYP1A2 (0.62) | CYP1A2GRM8GRM6GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112023539-B | Air purification filter core in car | 东风汽车集团有限公司 | 2021-12-17 | — | — | CN | claimed |
| CN-112023539-A | In-car air purification filter element and preparation method of carbon fiber paper in car air purification filter element | 东风汽车集团有限公司 | 2020-12-04 | — | — | CN | claimed |
| CN-110289120-B | Preparation and packaging method of composite sintered silver preformed sheet | 深圳市先进连接科技有限公司 | 2020-11-10 | — | — | CN | claimed |
| CN-112023539-B | Air purification filter core in car | 东风汽车集团有限公司 | 2021-12-17 | — | — | CN | disclosed |
| CN-112023539-A | In-car air purification filter element and preparation method of carbon fiber paper in car air purification filter element | 东风汽车集团有限公司 | 2020-12-04 | — | — | CN | disclosed |
| CN-110289120-B | Preparation and packaging method of composite sintered silver preformed sheet | 深圳市先进连接科技有限公司 | 2020-11-10 | — | — | CN | disclosed |
| US-6686133-B2 | CONTAINING LIGHT-INSENSITIVE SILVER SALTS OF ORGANIC CARBOXYLIC ACIDS WITH ONE OR MORE CARBOXYLIC ACID AND A BINDER, EXCLUSIVE OF SILVER SUCCINATE SIMILAR COMPOUNDS | AGFA-GEVAERT (BE) | 2004-02-03 | — | — | US | disclosed |
| WO-1991014015-A1 | METHOD AND MATERIALS FOR FORMING MULTI-LAYER CIRCUITS BY AN ADDITIVE PROCESS | OLIN CORPORATION (US) | 1991-09-19 | — | — | WO | disclosed |
| US-4232512-A | Solid state watch module construction | CITIZEN WATCH CO., LTD. (JP) | 1980-11-11 | — | — | US | disclosed |