Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of D-Glutamate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP known ✓ | O00591 | 2/20 | 0.50 |
| ▸ | GABRD known ✓ | O14764 | 2/20 | 0.50 |
| ▸ | GABRA1 known ✓ | P14867 | 2/20 | 0.50 |
| ▸ | GABRB1 known ✓ | P18505 | 2/20 | 0.50 |
| ▸ | GABRG2 known ✓ | P18507 | 2/20 | 0.50 |
| ▸ | GABRB3 known ✓ | P28472 | 2/20 | 0.50 |
| ▸ | GABRA5 known ✓ | P31644 | 2/20 | 0.50 |
| ▸ | GABRA3 known ✓ | P34903 | 2/20 | 0.50 |
| ▸ | GABRA2 known ✓ | P47869 | 2/20 | 0.50 |
| ▸ | GABRB2 known ✓ | P47870 | 2/20 | 0.50 |
| ▸ | GABRA4 known ✓ | P48169 | 2/20 | 0.50 |
| ▸ | GABRE known ✓ | P78334 | 2/20 | 0.50 |
| ▸ | GABRA6 known ✓ | Q16445 | 2/20 | 0.50 |
| ▸ | GABRG1 known ✓ | Q8N1C3 | 2/20 | 0.50 |
| ▸ | GABRG3 known ✓ | Q99928 | 2/20 | 0.50 |
| ▸ | GABRQ known ✓ | Q9UN88 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | GRM8 | O00222 | 1/20 | 0.62 |
| ▸ | GRM6 | O15303 | 1/20 | 0.62 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| D-Glutamate SCHEMBL1782280 | 1.00 | CYP1A2 (0.62) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL27981176 | 1.00 | CYP1A2 (0.62) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL541430 | 1.00 | CYP1A2 (0.62) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL16336 | 1.00 | CYP1A2 (0.62) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL23828179 | 0.98 | CYP1A2 (0.60) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL31067339 | 0.98 | GRM8 (0.60) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL2853216 | 0.98 | CYP1A2 (0.60) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL3781140 | 0.98 | CYP1A2 (0.60) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL317907 | 0.98 | CYP1A2 (0.60) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL30149979 | 0.98 | CYP1A2 (0.60) | CYP1A2GRM8GRM6GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1038 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116574720-A | Solid-state fermentation pickle microbial inoculum and preparation method thereof | 四川工商职业技术学院 | 2023-08-11 | — | — | CN | claimed |
| CN-115591585-A | Organic aluminum-SiO 2 Type aerogel catalyst and preparation method thereof | 贵州大学（CN） | 2023-01-13 | — | — | CN | claimed |
| CN-111592670-A | Preparation method of gamma-polyglutamic acid molecularly imprinted polymer membrane | 上海应用技术大学 | 2020-08-28 | — | — | CN | claimed |
| CN-110521883-A | A kind of Bullfrog feedstuff formula | ZHEJIANG HAIHUI BIOTECHNOLOGY CO LTD | 2019-12-03 | — | — | CN | claimed |
| CN-110506797-A | A kind of sandwich meat and preparation method thereof | JIANGJIANG ZHONGYANG FOOD CO LTD | 2019-11-29 | — | — | CN | claimed |
| CN-110447872-A | A kind of fresh walnut kernel can and preparation method thereof | LIU FAN | 2019-11-15 | — | — | CN | claimed |
| CN-110447832-A | A kind of dried duck meat processing technology | INNER MONGOLIA SAIFEIYA AGRICULTURAL SCIENCE AND TECH DEVELOPMENT CO LTD | 2019-11-15 | — | — | CN | claimed |
| CN-110384212-A | A kind of spicy duck wing product formula | 沈阳一合食品有限公司 | 2019-10-29 | — | — | CN | claimed |
| CN-110367469-A | A kind of pure mellow wine foie gras factory formula | 霍邱县仁俊食品有限公司 | 2019-10-25 | — | — | CN | claimed |
| CN-109965243-A | A kind of preparation method mixing pungent dish | 梅新建 | 2019-07-05 | — | — | CN | claimed |
| CN-1101155-C | Granular composite flavouring | ZHANG XU (CN) | 2003-02-12 | — | — | CN | claimed |
| CN-1386437-A | Method for cooking pig's trotters | MENG XIANJUN (CN) | 2002-12-25 | — | — | CN | claimed |
| CN-1266639-A | Granular composite flavouring | ZHANG XU (CN) | 2000-09-20 | — | — | CN | claimed |
| CN-1214938-A | Frozen dried heptitis A toxicity-reduced bio-vaccine and protective agent thereof | CHANGCHUN BIOLOG PRODUCTS I MI (CN) | 1999-04-28 | — | — | CN | claimed |
| CN-1193481-A | Prescription of fragrant instant mushroom and production thereof | REN QIYUN (CN) | 1998-09-23 | — | — | CN | claimed |
| CN-1181206-A | Method for prepn. of spiced jerky | WANG XINWEN (CN) | 1998-05-13 | — | — | CN | claimed |
| CN-1140031-A | Formula for | GAOGOU GROUP TIED TROTTERS FAC (CN) | 1997-01-15 | — | — | CN | claimed |
| CN-1084008-A | Composite growth regulator for edible fungus and its preparing process | LIU JINJUN (CN) | 1994-03-23 | — | — | CN | claimed |
| CN-1008533-B | MANUFACTURING COOKING WINES YELLOW WINES & BUBBLING WINES FROM ETHYL ALCOHOL WASTE LIQUOR | BEIJING CHEMICAL ENG (CN) | 1990-06-27 | — | — | CN | claimed |
| CN-1034575-A | Make cooking wine, yellow rice wine and light sparkling wine with alcohol slops | BEIJING CHEMICAL ENG (CN) | 1989-08-09 | — | — | CN | claimed |