Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7681925 | 0.82 | MMP1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL11529391 | 0.80 | DNM1 (0.35) | — | |
| SCHEMBL7115358 | 0.75 | FDPS (0.39) | FDPSKCNA5KCNH2 | |
| SCHEMBL335809 | 0.73 | — | — | |
| SCHEMBL1686729 | 0.73 | FDPS (0.42) | FDPSKCNA5KCNH2 | |
| SCHEMBL17520206 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL7371395 | 0.73 | FDPS (0.37) | FDPS | |
| SCHEMBL28282786 | 0.73 | MAPT (0.38) | — | |
| Hydrochloric Acid SCHEMBL216404 | 0.71 | — | — | |
| SCHEMBL172247 | 0.71 | FDPS (0.40) | FDPSKCNA5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040127499-A1 | Compounds, compositions and methods for preventing and treating pestivirus infection and associated diseases | PEVEAR DANIEL C | 2004-07-01 | — | — | US | disclosed |
| US-20030176431-A1 | Compounds, compositions and methods for preventing and treating pestivirus infection and associated diseases | PEVEAR DANIEL C | 2003-09-18 | — | — | US | disclosed |
| EP-0921803-A4 | METHODS FOR PREVENTING AND TREATING PESTIVIRUS INFECTION AND ASSOCIATED DISEASES | VIROPHARMA INC (US) | 2003-04-02 | — | — | EP | disclosed |
| US-6541472-B1 | 3-thio-5H-1,2,4-triazino(5,6-b) indole derivatives | VIROPHARMA INCORPORATED | 2003-04-01 | — | — | US | disclosed |
| EP-1056744-A1 | 6,9-DISUBSTITUTED 2- TRANS-(4- AMINOCYCLOHEXYL) AMINO]PURINES | Aventis Pharmaceuticals Inc. (US) | 2000-12-06 | — | — | EP | disclosed |
| WO-1999043675-A1 | 6,9-DISUBSTITUTED 2-[TRANS-(4- AMINOCYCLOHEXYL) AMINO]PURINES | AVENTIS PHARMACEUTICALS INC. (US) | 1999-09-02 | — | — | WO | disclosed |
| EP-0921803-A1 | METHODS FOR PREVENTING AND TREATING PESTIVIRUS INFECTION AND ASSOCIATED DISEASES | Viropharma Incorporated (US) | 1999-06-16 | — | — | EP | disclosed |
| US-5830894-A | USING A TRIAZINOINDOLE COMPOUND | VIROPHARMA INCORPORATED (US) | 1998-11-03 | — | — | US | disclosed |
| WO-1998047899-A1 | SUBSTITUTED PYRROLOPYRIDINES USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASES | ORTHO-MCNEIL CORPORATION, INC. (US) | 1998-10-29 | — | — | WO | disclosed |
| WO-1998036752-A1 | METHODS FOR PREVENTING AND TREATING PESTIVIRUS INFECTION AND ASSOCIATED DISEASES | VIROPHARMA INCORPORATED (US) | 1998-08-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176431-A1 | Compounds, compositions and methods for preventing and treating pestivirus infection and associated diseases | ZC3HAV1, MAVS, HAVCR2 | FDPS 58/4885KCNA5 1959/4885KCNH2 2336/4885 |
| US-20040127499-A1 | Compounds, compositions and methods for preventing and treating pestivirus infection and associated diseases | ZC3HAV1, MAVS, HAVCR2 | FDPS 58/4885KCNA5 1959/4885KCNH2 2336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.