SCHEMBL673967

SCHEMBL673967

CN(C)CCN=Cc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.49
MAP1LC3B Q9GZQ8 6/20 0.47
ALDH1A1 P00352 2/20 0.45
KMT2A Q03164 2/20 0.45
KDM4E B2RXH2 1/20 0.45
MEN1 O00255 1/20 0.45
TAAR1 Q96RJ0 2/20 0.43
LMNA P02545 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA9 Q16790 1/20 0.41
G6PC1 P35575 1/20 0.40
HTR2A P28223 1/20 0.39
HRH1 P35367 1/20 0.39
HTR6 P50406 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11558089 1.00 CA2 (0.49) CA2MAP1LC3BALDH1A1KMT2AKDM4E
SCHEMBL10616591 0.89 KDM4E (0.47) CA2MAP1LC3BALDH1A1KMT2AKDM4E
SCHEMBL10616595 0.89 KDM4E (0.47) CA2MAP1LC3BALDH1A1KMT2AKDM4E
SCHEMBL8635393 0.87 SIGMAR1 (0.46) CA2MAP1LC3BKMT2AKDM4EMEN1
SCHEMBL16073014 0.83 CA2 (0.52) CA2ALDH1A1KMT2AKDM4EMEN1
SCHEMBL4891588 0.83 CA2 (0.52) CA2ALDH1A1KMT2AKDM4EMEN1
SCHEMBL23890392 0.83 CA2 (0.45) CA2MAP1LC3BALDH1A1KMT2AKDM4E
SCHEMBL673024 0.81 ALDH1A1 (0.47) CA2ALDH1A1KMT2AKDM4EMEN1
SCHEMBL845363 0.80 CA2 (0.61) CA2ALDH1A1KMT2AKDM4EMEN1
SCHEMBL845362 0.80 CA2 (0.61) CA2ALDH1A1KMT2AKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1873168-B1 MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES BRIDGESTONE CORP (JP) 2012-12-12 EP claimed
US-7968652-B2 Modified conjugated diene copolymer, rubber compositions and tires BRIDGESTONE CORPORATION (JP) 2011-06-28 US claimed
US-7671136-B2 Modified polymers prepared with lanthanide-based catalysts BRIDGESTONE CORPORATION (JP) 2010-03-02 US claimed
US-20090292043-A1 MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES BRIDGESTONE CORPORATION (JP) 2009-11-26 US claimed
EP-1873168-A1 MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES Bridgestone Corporation (JP) 2008-01-02 EP claimed
US-20060025539-A1 Modified polymers prepared with lanthanide-based catalysts OZAWA YOICHI 2006-02-02 US claimed
US-6977281-B1 Modified polymers prepared with lanthanide-based catalysts BRIDGESTONE CORPORATION (JP) 2005-12-20 US claimed
EP-1237935-A1 MODIFIED POLYMERS PREPARED WITH LANTHANIDE-BASED CATALYSTS Bridgestone Corporation (JP) 2002-09-11 EP claimed
WO-2001034659-A1 MODIFIED POLYMERS PREPARED WITH LANTHANIDE-BASED CATALYSTS BRIDGESTONE CORPORATION (JP) 2001-05-17 WO claimed
US-11680153-B2 Rubber composition LG CHEM, LTD. 2023-06-20 US disclosed
CN-111051361-B Rubber composition 株式会社LG化学 2023-06-20 CN disclosed
EP-3715388-B1 MODIFIED CONJUGATED DIENE-BASED POLYMER AND METHOD FOR PREPARING THE SAME LG CHEMICAL LTD (KR) 2023-04-26 EP disclosed
US-11421053-B2 Conjugated diene-based polymer and method for preparing the same LG CHEM, LTD. 2022-08-23 US disclosed
US-11384178-B2 2022-07-12 US disclosed
US-5227431-A DIENE POLYMERS AND COPOLYMERS JUMPED BY PARTIAL CROSSLINKING AND TERMINATED WITH A SUBSTITUTED IMINE BRIDGESTONE/FIRESTONE, INC. (US) 1993-07-13 US disclosed
EP-0510410-A1 Diene polymers and copolymers jumped by partial coupling and terminated with a substituted imine BRIDGESTONE/FIRESTONE, INC. (US) 1992-10-28 EP disclosed
US-5109907-A Tire treads with reduced rolling resistance BRIDGESTONE/FIRESTONE, INC. (US) 1992-05-05 US disclosed
US-5066729-A Tire Treads BRIDGESTONE/FIRESTONE, INC. (US) 1991-11-19 US disclosed
EP-0451604-A2 Diene polymers and copolymers terminated by reaction with n-alkyl and n-aryl imines BRIDGESTONE/FIRESTONE, INC. (US) 1991-10-16 EP disclosed
US-4174317-A ANTIINFLAMMATORY AGENTS E. R. SQUIBB & SONS, INC. (US) 1979-11-13 US disclosed