Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 5/20 | 0.41 |
| ▸ | CA9 | Q16790 | 4/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10616595 | 0.95 | KDM4E (0.47) | SIGMAR1CA2KDM4EHTR2AHRH1 | |
| SCHEMBL10616591 | 0.95 | KDM4E (0.47) | SIGMAR1CA2KDM4EHTR2AHRH1 | |
| SCHEMBL673967 | 0.87 | CA2 (0.49) | CA2KDM4EHTR2AHRH1MEN1 | |
| SCHEMBL11558089 | 0.87 | CA2 (0.49) | CA2KDM4EHTR2AHRH1MEN1 | |
| SCHEMBL674665 | 0.83 | SIGMAR1 (0.49) | SIGMAR1CA2KDM4EMEN1KMT2A | |
| SCHEMBL11760622 | 0.82 | CA2 (0.55) | CA2KDM4EMEN1KMT2ACA12 | |
| SCHEMBL10899339 | 0.82 | CA2 (0.55) | CA2KDM4EMEN1KMT2ACA12 | |
| SCHEMBL10899334 | 0.82 | CA2 (0.55) | CA2KDM4EMEN1KMT2ACA12 | |
| SCHEMBL15172983 | 0.82 | CA2 (0.55) | CA2KDM4EMEN1KMT2ACA12 | |
| SCHEMBL12460453 | 0.82 | CA2 (0.55) | CA2KDM4EMEN1KMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102245694-A | Rubber composition for tread and tire using the same | BRIDGESTONE CORP | 2011-11-16 | — | — | CN | disclosed |
| EP-0622381-B1 | Anionic polymerization initiators and reduced hysteresis products therefrom | BRIDGESTONE CORP (JP) | 1998-07-29 | — | — | EP | disclosed |
| EP-0639587-B1 | Diene polymers and copolymers terminated with compounds having multiple-bonded nitrogen atoms and partially crosslinked with polyfunctional reagents | BRIDGESTONE FIRESTONE INC (US) | 1997-10-22 | — | — | EP | disclosed |
| EP-0510410-B1 | Diene polymers and copolymers jumped by partial coupling and terminated with a substituted imine | BRIDGESTONE FIRESTONE INC (US) | 1996-06-12 | — | — | EP | disclosed |
| EP-0639587-A1 | Diene polymeres and copolymers terminated with compounds having multiple-bonded nitrogen atoms and partially crosslinked with polyfunctional reagents | BRIDGESTONE/FIRESTONE, INC. (US) | 1995-02-22 | — | — | EP | disclosed |
| EP-0451604-B1 | Diene polymers and copolymers terminated by reaction with n-alkyl and n-aryl imines | BRIDGESTONE FIRESTONE INC (US) | 1994-12-21 | — | — | EP | disclosed |
| EP-0622381-A1 | Anionic polymerization initiators and reduced hysteresis products therefrom | BRIDGESTONE CORPORATION (JP) | 1994-11-02 | — | — | EP | disclosed |
| US-5310798-A | Tire treads | BRIDGESTONE/FIRESTONE, INC. (US) | 1994-05-10 | — | — | US | disclosed |
| US-5227431-A | DIENE POLYMERS AND COPOLYMERS JUMPED BY PARTIAL CROSSLINKING AND TERMINATED WITH A SUBSTITUTED IMINE | BRIDGESTONE/FIRESTONE, INC. (US) | 1993-07-13 | — | — | US | disclosed |
| EP-0510410-A1 | Diene polymers and copolymers jumped by partial coupling and terminated with a substituted imine | BRIDGESTONE/FIRESTONE, INC. (US) | 1992-10-28 | — | — | EP | disclosed |
| US-5109907-A | Tire treads with reduced rolling resistance | BRIDGESTONE/FIRESTONE, INC. (US) | 1992-05-05 | — | — | US | disclosed |
| US-5066729-A | Tire Treads | BRIDGESTONE/FIRESTONE, INC. (US) | 1991-11-19 | — | — | US | disclosed |
| EP-0451604-A2 | Diene polymers and copolymers terminated by reaction with n-alkyl and n-aryl imines | BRIDGESTONE/FIRESTONE, INC. (US) | 1991-10-16 | — | — | EP | disclosed |