Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 10/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | PPOX | P50336 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | GAK | O14976 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | FLT1 | P17948 | 1/20 | 0.32 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.32 |
| ▸ | EPHA4 | P54764 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6745479 | 0.86 | NPC1 (0.38) | LRRK2HSP90AA1HSP90AB1ALOX5APFEN1 | |
| SCHEMBL6745490 | 0.85 | LRRK2 (0.41) | LRRK2HSP90AA1HSP90AB1 | |
| SCHEMBL6740532 | 0.84 | PGK1 (0.37) | KDR | |
| SCHEMBL6743960 | 0.82 | KDM4E (0.33) | ALOX5APFEN1 | |
| SCHEMBL6742514 | 0.82 | COMT (0.34) | — | |
| SCHEMBL6745483 | 0.81 | HSP90AA1 (0.40) | LRRK2HSP90AA1HSP90AB1PTK2AURKA | |
| SCHEMBL7672722 | 0.81 | KDM4E (0.40) | HSP90AA1ALOX5APFEN1 | |
| SCHEMBL6742533 | 0.78 | ASPH (0.41) | — | |
| SCHEMBL6175607 | 0.78 | ALDH1A1 (0.46) | ALOX5APFEN1 | |
| SCHEMBL7681163 | 0.77 | HSP90AA1 (0.39) | HSP90AA1HSP90AB1PPOXSRCGAK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040043903-A1 | Herbicides; applying to plants | BASF AKTIENGESELLSCHAFT (DE) | 2004-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040043903-A1 | Herbicides; applying to plants | DDT, DRD1, DRD4 | LRRK2 3170/4885HSP90AA1 439/4885HSP90AB1 420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.