SCHEMBL6742533

SCHEMBL6742533

Cc1c(C(F)(F)F)cnc(-c2cc(C(=O)O)c(Cl)cc2F)c1Cl

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ASPH Q12797 1/20 0.41
RORC P51449 8/20 0.36
DHODH Q02127 2/20 0.36
NOTUM Q6P988 2/20 0.36
SCN9A Q15858 3/20 0.34
NTRK1 P04629 2/20 0.34
CLCN2 P51788 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6742688 0.85 SCN9A (0.33) SCN9ANPC1RAB9A
SCHEMBL6742514 0.83 COMT (0.34) RORC
SCHEMBL6740866 0.81 MAPK1 (0.35) SCN9ANPC1RAB9A
SCHEMBL6743960 0.80 KDM4E (0.33)
SCHEMBL6739675 0.78 LRRK2 (0.36)
SCHEMBL4066356 0.78 ALDH1A1 (0.47) NPC1RAB9A
SCHEMBL6745488 0.75 MAPK1 (0.36) RORCSCN9A
SCHEMBL6743036 0.75 HSD11B1 (0.40)
SCHEMBL6745504 0.75 HSD11B1 (0.48)
SCHEMBL8546587 0.74 RORC (0.36) RORCNOTUMSCN9ANTRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040043903-A1 Herbicides; applying to plants BASF AKTIENGESELLSCHAFT (DE) 2004-03-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040043903-A1 Herbicides; applying to plants DDT, DRD1, DRD4 ASPH 1447/4885RORC 3108/4885DHODH 104/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.