Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.48 |
| ▸ | PRKCA | P17252 | 2/20 | 0.46 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.46 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.43 |
| ▸ | DGKA | P23743 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18204276 | 0.93 | LMNA (0.47) | SLC6A5PRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL6740155 | 0.91 | SLC6A5 (0.51) | SLC6A5PRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL3371269 | 0.88 | SLC6A5 (0.53) | SLC6A5PRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL5824303 | 0.84 | SLC6A5 (0.50) | SLC6A5PRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL1800357 | 0.84 | MAPT (0.48) | SLC6A5PRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL29449493 | 0.81 | SLC6A5 (0.54) | SLC6A5PRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL14809228 | 0.81 | SLC6A5 (0.51) | SLC6A5PRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL26134552 | 0.81 | SLC6A5 (0.51) | SLC6A5PRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL22319402 | 0.81 | SLC6A5 (0.54) | SLC6A5PRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL7632420 | 0.80 | SLC6A5 (0.53) | SLC6A5PRKCAPRKCEPRKCQPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3279300-B1 | FRAGRANCE COMPOSITION | KAO CORP (JP) | 2019-03-27 | — | — | EP | disclosed |
| EP-3279300-A1 | FRAGRANCE COMPOSITION | KAO CORPORATION (JP) | 2018-02-07 | — | — | EP | disclosed |
| EP-2857482-B1 | PERFUME COMPOSITION | KAO CORP (JP) | 2017-10-11 | — | — | EP | disclosed |
| US-9567550-B2 | Fragrance composition | KAO CORPORATION (JP) | 2017-02-14 | — | — | US | disclosed |
| US-20160376521-A1 | PERFUME COMPOSITION | KAO CORPORATION (JP) | 2016-12-29 | — | — | US | disclosed |
| US-20160326457-A1 | ESTER | KAO CORPORATION (JP) | 2016-11-10 | — | — | US | disclosed |
| EP-3075822-A1 | PERFUME COMPOSITION | Kao Corporation (JP) | 2016-10-05 | — | — | EP | disclosed |
| EP-3072877-A1 | ESTER | Kao Corporation (JP) | 2016-09-28 | — | — | EP | disclosed |
| US-20150118174-A1 | FRAGRANCE COMPOSITION | KAO CORPORATION (JP) | 2015-04-30 | — | — | US | disclosed |
| EP-2857482-A1 | PERFUME COMPOSITION | Kao Corporation (JP) | 2015-04-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150118174-A1 | FRAGRANCE COMPOSITION | FAAH2, FAAH, DACH1 | SLC6A5 3896/4885PRKCA 4084/4885PRKCE 3414/4885 |
| US-20160376521-A1 | PERFUME COMPOSITION | DEGS1, ALG3, DHCR24 | SLC6A5 4110/4885PRKCA 2622/4885PRKCE 1488/4885 |
| US-20160326457-A1 | ESTER | MEP1A, ELOVL1, EBP | SLC6A5 4398/4885PRKCA 1635/4885PRKCE 487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.