SCHEMBL674090

SCHEMBL674090

CC(c1cc(Cl)cc(Cl)c1)c1cc(Cl)cc(Cl)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
GABRA1 P14867 1/20 0.40
GABRB1 P18505 1/20 0.40
TP53 P04637 2/20 0.38
CYP3A4 P08684 2/20 0.38
ADRB2 P07550 1/20 0.36
IDO1 P14902 1/20 0.35
TDO2 P48775 1/20 0.35
ALDH1A1 P00352 3/20 0.33
GRN P28799 1/20 0.33
SORT1 Q99523 1/20 0.33
CYP1A2 P05177 1/20 0.33
POLB P06746 1/20 0.33
CYP2C19 P33261 1/20 0.33
ESR1 P03372 1/20 0.33
PDCD1 Q15116 1/20 0.33
ESR2 Q92731 1/20 0.33
CD274 Q9NZQ7 1/20 0.33
CNR1 P21554 1/20 0.32
CNR2 P34972 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17071879 0.85 IDO1 (0.50) TSHRIDO1TDO2ALDH1A1CNR2
SCHEMBL17069291 0.85 IDO1 (0.50) TSHRIDO1TDO2ALDH1A1CNR2
SCHEMBL17069289 0.85 IDO1 (0.50) TSHRIDO1TDO2ALDH1A1CNR2
SCHEMBL422198 0.81 TSHR (0.50) TSHRGABRA1GABRB1TP53CYP3A4
Ammonia Solution, Strong SCHEMBL5999637 0.80 CYP19A1 (0.45) CYP3A4ALDH1A1CYP2C19ESR1PDCD1
SCHEMBL16099813 0.79 TSHR (0.47) TSHRGABRA1GABRB1TP53CYP3A4
Ammonia Solution, Strong SCHEMBL5676040 0.79 TSHR (0.47) TSHRGABRA1GABRB1TP53CYP3A4
SCHEMBL17418027 0.79 TSHR (0.47) TSHRGABRA1GABRB1TP53CYP3A4
SCHEMBL16099814 0.79 TSHR (0.47) TSHRGABRA1GABRB1TP53CYP3A4
SCHEMBL12204680 0.77 ESR1 (0.34) ADRB2ESR1PDCD1ESR2CD274

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 867 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5357027-A Fireproof, heat resistant, impact resistant molding materials IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1994-10-18 US claimed
US-20260146128-A1 POLYCARBONATE COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES COMPRISING THE POLYCARBONATE COMPOSITION SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2026-05-28 US disclosed
US-20260132240-A1 LINEAR BLOCK COPOLYMER AND CURABLE THERMOSETTING COMPOSITION COMPRISING THE LINEAR BLOCK COPOLYMER SHPP GLOBAL TECH B V (NL) 2026-05-14 US disclosed
EP-4720194-A1 POLYCARBONATE COPOLYMER COMPOSITIONS SHPP Global Technologies B.V. (NL) 2026-04-08 EP disclosed
EP-4605473-B1 POLYCARBONATE COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES COMPRISING THE POLYCARBONATE COMPOSITION SHPP GLOBAL TECH BV (NL) 2026-04-01 EP disclosed
EP-4716968-A1 BATTERY PACK COVER WITH A PROTRUDING DOUBLE WALL BATTERY DIVIDER AND THERMAL RUNAWAY BARRIER SABIC Global Technologies B.V. (NL) 2026-04-01 EP disclosed
EP-4684445-A1 BATTERY PACK WITH BATTERY MODULE PARTIALLY SUBMERGED IN COOLANT SABIC Global Technologies B.V. (NL) 2026-01-28 EP disclosed
US-20260002025-A1 POLYCARBONATE COMPOSITION, ARTICLES FORMED THEREFORE, AND METHODS FOR THE MANUFACTURE THEREOF SHPP GLOBAL TECH BV (NL) 2026-01-01 US disclosed
US-12503593-B2 Curable thermosetting composition including poly(arylene ether) copolymer SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2025-12-23 US disclosed
EP-4663691-A1 COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES COMPRISING THE COMPOSITION SHPP Global Technologies B.V. (NL) 2025-12-17 EP disclosed
US-4086212-A ESTERIFICATION OR TRANSESTERIFICATION BAYER AKTIENGESELLSCHAFT (DT) 1978-04-25 US disclosed
US-4024093-A Flame retardant polyphenylene ether resin compositions containing a halogenated flame retardant and selected organic iron salts GENERAL ELECTRIC COMPANY (US) 1977-05-17 US disclosed
US-4020124-A Blends of a polyphenylene ether resin, alkenyl aromatic resins modified with EPDM rubber and graft polymerized high rubber content polymers GENERAL ELECTRIC COMPANY (US) 1977-04-26 US disclosed
US-4013613-A INCLUDING ADDITION POLYMER GENERAL ELECTRIC COMPANY (US) 1977-03-22 US disclosed
US-4002581-A MOLDINGS GENERAL ELECTRIC COMPANY (US) 1977-01-11 US disclosed
US-3981841-A MOLDING MATERIALS, IMPACT STRENGTH GENERAL ELECTRIC COMPANY (US) 1976-09-21 US disclosed
US-3974235-A Blends of a polyphenylene ether resin, alkenyl aromatic resins modified with EPDM rubber and flame retardant GENERAL ELECTRIC COMPANY (US) 1976-08-10 US disclosed
US-3959211-A ETHYLENE-ALPHA-OLEFIN-DIENE GENERAL ELECTRIC COMPANY (US) 1976-05-25 US disclosed
US-3953394-A POLYETHYLENE TEREPHTHALATE-POLYBUTYLENE TEREPHTHALATE BLENDS GENERAL ELECTRIC COMPANY (US) 1976-04-27 US disclosed
US-3943191-A MOLDING GENERAL ELECTRIC COMPANY (US) 1976-03-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260146128-A1 POLYCARBONATE COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES COMPRISING THE POLYCARBONATE COMPOSITION CYP46A1, RPTOR, PCNA TSHR 3048/4885GABRA1 3181/4885GABRB1 3043/4885
US-20260002025-A1 POLYCARBONATE COMPOSITION, ARTICLES FORMED THEREFORE, AND METHODS FOR THE MANUFACTURE THEREOF LCP1, COL2A1, SHBG TSHR 2616/4885GABRA1 2604/4885GABRB1 2658/4885
US-20260132240-A1 LINEAR BLOCK COPOLYMER AND CURABLE THERMOSETTING COMPOSITION COMPRISING THE LINEAR BLOCK COPOLYMER CBLB, UBE4A, PSMD14 TSHR 4263/4885GABRA1 1051/4885GABRB1 355/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.