SCHEMBL6740987

SCHEMBL6740987

O=C(c1ccccc1)c1ccsn1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.50
KMT2A Q03164 4/20 0.50
MEN1 O00255 3/20 0.47
NPC1 O15118 3/20 0.47
RAB9A P51151 3/20 0.47
MAPT P10636 3/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
PKM P14618 1/20 0.47
HPGD P15428 1/20 0.47
CNR2 P34972 1/20 0.46
HPGDS O60760 1/20 0.46
ATM Q13315 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
SRD5A2 P31213 1/20 0.43
LMNA P02545 3/20 0.42
ADORA2A P29274 1/20 0.42
ADORA1 P30542 1/20 0.42
USP2 O75604 1/20 0.42
GLA P06280 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2754190 0.83 NPC1 (0.50) KMT2AMEN1NPC1RAB9ALMNA
SCHEMBL675975 0.76
Hydrochloric Acid SCHEMBL7070954 0.74
SCHEMBL5572448 0.72 RAB9A (0.73) ALDH1A1KMT2ANPC1RAB9AMAPT
SCHEMBL5604467 0.70 KMT2A (0.63) ALDH1A1KMT2AMEN1NPC1RAB9A
SCHEMBL11493724 0.70
Benzophenone SCHEMBL30537001 0.69 ALDH1A1 (1.00) ALDH1A1KMT2AMEN1NPC1RAB9A
Benzophenone SCHEMBL6061130 0.69 ALDH1A1 (1.00) ALDH1A1KMT2AMEN1NPC1RAB9A
Benzophenone SCHEMBL30536983 0.69 ALDH1A1 (1.00) ALDH1A1KMT2AMEN1NPC1RAB9A
Benzophenone SCHEMBL28491203 0.69 ALDH1A1 (1.00) ALDH1A1KMT2AMEN1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101013080-B Sheath liquid for particle analyzer, method of preparing sheath liquid and particle analytic method using the sheath liquid SYSMEX CORP 2012-12-12 CN disclosed
CN-101013080-A Sheath liquid for particle analyzer, method of preparing sheath liquid and particle analytic method using the sheath liquid SYSMEX CORP (JP) 2007-08-08 CN disclosed
US-20040023807-A1 3-Arylisothiazoles and their use as herbicides BASF AKTIENGESELLSCHAFT (DE) 2004-02-05 US disclosed
US-6083879-A Herbicidal benzoylisothiazoles BASF AKTIENGESELLSCHAFT (DE) 2000-07-04 US disclosed
US-6083879-A Herbicidal benzoylisothiazoles BASF AKTIENGESELLSCHAFT (DE) 2000-07-04 US disclosed
US-6046137-A FOR CONTROLLING WEEDS BASF AKTIENGESELLSCHAFT (DE) 2000-04-04 US disclosed
US-6046137-A FOR CONTROLLING WEEDS BASF AKTIENGESELLSCHAFT (DE) 2000-04-04 US disclosed
US-5945381-A Herbicidal heterocyclically annulated benzoylisothiazoles BASF AKTIENGESELLSCHAFT (DE) 1999-08-31 US disclosed
US-5945381-A Herbicidal heterocyclically annulated benzoylisothiazoles BASF AKTIENGESELLSCHAFT (DE) 1999-08-31 US disclosed
EP-0898570-A1 HERBICIDAL HETEROCYCLICALLY SUBSTITUTED BENZOYLISOTHIAZOLES BASF AKTIENGESELLSCHAFT (DE) 1999-03-03 EP disclosed
EP-0897385-A1 HERBICIDAL HETEROCYCLICALLY ANNULATED BENZOYLISOTHIAZOLES BASF AKTIENGESELLSCHAFT (DE) 1999-02-24 EP disclosed
EP-0897384-A1 HERBICIDAL BENZOYLISOTHIAZOLES BASF AKTIENGESELLSCHAFT (DE) 1999-02-24 EP disclosed
WO-1997038987-A1 HERBICIDAL BENZOYLISOTHIAZOLES BASF AKTIENGESELLSCHAFT (DE) 1997-10-23 WO disclosed
WO-1997038996-A1 HERBICIDAL HETEROCYCLICALLY SUBSTITUTED BENZOYLISOTHIAZOLES BASF AKTIENGESELLSCHAFT (DE) 1997-10-23 WO disclosed
WO-1997038988-A1 HERBICIDAL HETEROCYCLICALLY ANNULATED BENZOYLISOTHIAZOLES BASF AKTIENGESELLSCHAFT (DE) 1997-10-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040023807-A1 3-Arylisothiazoles and their use as herbicides DDT, HAX1, SULT1E1 ALDH1A1 142/4885KMT2A 1009/4885MEN1 4560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.