Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.73 |
| ▸ | NPC1 | O15118 | 4/20 | 0.73 |
| ▸ | LMNA | P02545 | 1/20 | 0.73 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2859096 | 0.75 | LMNA (0.73) | RAB9ANPC1LMNAPOLBKMT2A | |
| SCHEMBL22246649 | 0.75 | NPC1 (0.61) | RAB9ANPC1LMNAPOLBKMT2A | |
| SCHEMBL15347911 | 0.73 | POLB (1.00) | RAB9ANPC1LMNAPOLBKMT2A | |
| SCHEMBL30834279 | 0.73 | RAB9A (0.73) | RAB9ANPC1POLBKMT2AALDH1A1 | |
| SCHEMBL231897 | 0.72 | KDR (0.78) | RAB9ANPC1POLBKMT2AKDM4E | |
| SCHEMBL6740987 | 0.72 | ALDH1A1 (0.50) | RAB9ANPC1LMNAKMT2AALDH1A1 | |
| SCHEMBL22725202 | 0.71 | POLB (0.53) | RAB9ANPC1LMNAPOLBKMT2A | |
| SCHEMBL20273850 | 0.71 | POLB (0.53) | RAB9ANPC1LMNAPOLBKMT2A | |
| SCHEMBL11204841 | 0.71 | SMN1; SMN2 (0.47) | RAB9ANPC1LMNAKMT2AALDH1A1 | |
| SCHEMBL9896549 | 0.70 | POLB (0.61) | RAB9ANPC1POLBKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230240299-A1 | COMPOSITION FOR CONTROLLING SUGAR BEET CERCOSPORA LEAF SPOT DISEASE | BAYER AKTIENGESELLSCHAFT (DE) | 2023-08-03 | — | — | US | disclosed |
| US-20070060551-A1 | Methods of using isothiazole derivatives to treat cancer or inflammation | QLT, INC. (CA) | 2007-03-15 | — | — | US | disclosed |
| EP-1521577-A1 | METHODS OF USING ISOTHIAZOLE DERIVATIVES TO TREAT CANCER OR INFLAMMATION | QLT, Inc. (CA) | 2005-04-13 | — | — | EP | disclosed |
| WO-2003105843-A1 | METHODS OF USING ISOTHIAZOLE DERIVATIVES TO TREAT CANCER OR INFLAMMATION | KINETEK PHARMACEUTICALS, INC. (CA) | 2003-12-24 | — | — | WO | disclosed |
| EP-0073973-A1 | Thiazolyl and isothiazolyl-carboxylic-acid anilides, process for their preparation and their utilization as fungicides | BASF Aktiengesellschaft (DE) | 1983-03-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060551-A1 | Methods of using isothiazole derivatives to treat cancer or inflammation | CASP3, LITAF, MGST3 | RAB9A 4306/4885NPC1 2350/4885LMNA 4700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.