SCHEMBL6741450

SCHEMBL6741450

CC(C)(C)OC(=O)Nc1c(C(F)(F)F)cnc(OCc2ccccc2)c1Cl

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.42
PTGER1 P34995 1/20 0.42
LMNA P02545 1/20 0.42
POLB P06746 1/20 0.42
MRGPRX4 Q96LA9 2/20 0.40
ATR Q13535 1/20 0.39
P2RX7 Q99572 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
RORC P51449 2/20 0.38
SCD O00767 1/20 0.37
SYK P43405 1/20 0.37
PPARA Q07869 1/20 0.37
GRIN2B Q13224 1/20 0.37
MCL1 Q07820 1/20 0.37
BAK1 Q16611 1/20 0.37
MEN1 O00255 1/20 0.37
NPC1 O15118 1/20 0.37
GAA P10253 1/20 0.37
RAB9A P51151 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6739678 0.76 MRGPRX4 (0.49) PTGER1MRGPRX4MCL1BAK1RXRA
SCHEMBL6740837 0.75 L3MBTL1 (0.42) LMNAMRGPRX4MCL1BAK1MEN1
SCHEMBL30512447 0.74 LMNA (0.44) CYP2C9PTGER1LMNAPOLBMRGPRX4
SCHEMBL25379391 0.74 LMNA (0.44) CYP2C9PTGER1LMNAPOLBMRGPRX4
SCHEMBL29165959 0.72 MRGPRX4 (0.40) MRGPRX4PPARARXRARXRBRXRG
SCHEMBL26608417 0.70 CYP2C9 (0.52) CYP2C9PTGER1P2RX7SCDMCL1
SCHEMBL24582782 0.70 CYP2C9 (0.52) CYP2C9PTGER1P2RX7SCDSYK
SCHEMBL29165910 0.70 PDK1 (0.40) MRGPRX4RORCMEN1KMT2ARXRA
SCHEMBL2894833 0.70 NPC1 (0.50) CYP2C9PTGER1LMNAMRGPRX4SMN1; SMN2
SCHEMBL10515590 0.70 PTGER1 (0.54) CYP2C9PTGER1SCDSYKPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040043903-A1 Herbicides; applying to plants BASF AKTIENGESELLSCHAFT (DE) 2004-03-04 US disclosed
EP-1335903-A1 2-ARYL-5-TRIFLUOROMETHYLPYRIDINES BASF AKTIENGESELLSCHAFT (DE) 2003-08-20 EP disclosed
WO-2002042275-A1 2-ARYL-5-TRIFLUOROMETHYLPYRIDINES BASF AKTIENGESELLSCHAFT (DE) 2002-05-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040043903-A1 Herbicides; applying to plants DDT, DRD1, DRD4 CYP2C9 144/4885PTGER1 3916/4885LMNA 4573/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.