Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HTR7 | P34969 | 6/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | CASR | P41180 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6739809 | 0.83 | GAA (0.58) | ALDH1A1HSD17B10KDM1AGAARCOR1 | |
| SCHEMBL20510979 | 0.82 | ALDH1A1 (0.69) | ALDH1A1HTR7ADRA1DADRA1AADRA1B | |
| SCHEMBL20511109 | 0.79 | ALDH1A1 (0.52) | ALDH1A1HTR7HSD17B10ADRA1DADRA1A | |
| SCHEMBL3267038 | 0.73 | LMNA (0.45) | ALDH1A1HSD17B10GAASMN1; SMN2KDM4E | |
| SCHEMBL5480527 | 0.72 | KMT2A (0.49) | ALDH1A1HSD17B10KDM1AGAARCOR1 | |
| SCHEMBL7772573 | 0.70 | CHRM2 (0.55) | ALDH1A1ADRA1DADRA1AADRA1BSMN1; SMN2 | |
| SCHEMBL14544593 | 0.70 | HTR1A (0.54) | ALDH1A1HTR7HSD17B10ADRA1DADRA1A | |
| SCHEMBL32675853 | 0.70 | HTR7 (0.73) | ALDH1A1HTR7ADRA1DADRA1AADRA1B | |
| SCHEMBL34462910 | 0.70 | CYP1A2 (0.60) | ALDH1A1HSD17B10KDM1AGAARCOR1 | |
| SCHEMBL3113286 | 0.70 | CYP1A2 (0.70) | ALDH1A1HSD17B10SMN1; SMN2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040082627-A1 | Certain aromatic monocycles as kinase modulators | CGI PHARMACEUTICALS, INC. | 2004-04-29 | — | — | US | disclosed |
| WO-2004000820-A2 | CERTAIN AROMATIC MONOCYCLES AS KINASE MODULATORS | CELLULAR GENOMICS, INC. (US) | 2003-12-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082627-A1 | Certain aromatic monocycles as kinase modulators | MAP3K20, MAP3K1, MAP3K19 | ALDH1A1 2999/4885HTR7 1900/4885HSD17B10 2627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.