SCHEMBL6743041

SCHEMBL6743041

Nc1cccc(Oc2cccc(-c3ccccc3)c2Oc2cccc(N)c2O)c1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.44
HSD17B10 Q99714 2/20 0.44
NCOA1 Q15788 1/20 0.41
NCOA3 Q9Y6Q9 1/20 0.41
KDM4E B2RXH2 1/20 0.39
MAPT P10636 1/20 0.39
CRHBP P24387 1/20 0.39
CRHR2 Q13324 1/20 0.39
HNF4A P41235 1/20 0.37
HPGD P15428 1/20 0.36
BCL2L1 Q07817 1/20 0.36
HDAC4 P56524 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
BRD4 O60885 1/20 0.36
NR1I2 O75469 1/20 0.36
SMARCA2 P51531 1/20 0.36
SMARCA4 P51532 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL560390 0.87 KDM4E (0.52) ALDH1A1HSD17B10NCOA1NCOA3KDM4E
SCHEMBL6734541 0.81 ALDH1A1 (0.41) ALDH1A1HSD17B10NCOA1NCOA3KDM4E
SCHEMBL713603 0.80 ALDH1A1 (0.50) ALDH1A1HSD17B10NCOA1NCOA3MAPT
SCHEMBL565066 0.79 MMP2 (0.45) ALDH1A1HSD17B10KDM4EMAPTCRHBP
SCHEMBL4625340 0.77 HDAC4 (0.52) ALDH1A1HSD17B10NCOA1NCOA3HNF4A
SCHEMBL27966488 0.77 NCOA1 (0.47) ALDH1A1HSD17B10NCOA1NCOA3KDM4E
SCHEMBL30646075 0.75 ALDH1A1 (0.62) ALDH1A1HSD17B10KDM4EMAPTHNF4A
SCHEMBL565298 0.75 ALDH1A1 (0.62) ALDH1A1HSD17B10KDM4EMAPTHNF4A
SCHEMBL11833814 0.75 NCOA1 (0.51) ALDH1A1NCOA1NCOA3L3MBTL1BRD4
SCHEMBL4952643 0.75 AR (0.40) ALDH1A1HSD17B10NCOA1NCOA3KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6686106-B2 POLYIMIDESILOXANE COPOLYMERS UBE INDUSTRIES, LTD. (JP) 2004-02-03 US disclosed
US-20020001763-A1 Photosensitive resin compositions, insulating films, and processes for formation of the films UBE INDUSTRIES, LTD. 2002-01-03 US disclosed
US-5643986-A STORAGE STABLE, PROTECTIVE FILMS UBE INDUSTRIES, LTD. (JP) 1997-07-01 US disclosed