SCHEMBL6734541

SCHEMBL6734541

Nc1cccc(Oc2cccc(-c3ccccc3)c2Oc2cccc(N)c2C(=O)O)c1C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
HSD17B10 Q99714 1/20 0.41
TDP1 Q9NUW8 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
FABP3 P05413 2/20 0.39
FABP7 O15540 1/20 0.39
FABP5 Q01469 1/20 0.39
NCOA1 Q15788 1/20 0.39
NCOA3 Q9Y6Q9 1/20 0.39
FOLH1 Q04609 1/20 0.38
HNF4A P41235 1/20 0.37
RXRA P19793 1/20 0.37
RXRB P28702 1/20 0.37
RXRG P48443 1/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA7 P43166 1/20 0.37
CA9 Q16790 1/20 0.37
CA14 Q9ULX7 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28415540 0.90 NCOA1 (0.49) ALDH1A1HSD17B10TDP1L3MBTL1FABP3
SCHEMBL10699812 0.84 HNF4A (0.49) ALDH1A1HSD17B10TDP1L3MBTL1FABP3
SCHEMBL560390 0.83 KDM4E (0.52) ALDH1A1HSD17B10TDP1L3MBTL1NCOA1
SCHEMBL7713669 0.83 CA12 (0.50) CA12CA1CA2CA7CA9
SCHEMBL6743041 0.81 ALDH1A1 (0.44) ALDH1A1HSD17B10TDP1L3MBTL1FABP3
SCHEMBL9184764 0.81 LTB4R (0.42) TDP1L3MBTL1FABP3FABP7FABP5
SCHEMBL713318 0.79 HTT (0.54) ALDH1A1HSD17B10TDP1L3MBTL1FABP3
SCHEMBL1535068 0.78 ALDH1A1 (0.56) ALDH1A1HSD17B10L3MBTL1FABP3FABP5
SCHEMBL31212993 0.78 ALDH1A1 (0.56) ALDH1A1HSD17B10L3MBTL1FABP3FABP5
SCHEMBL3178426 0.78 ALDH1A1 (0.37) ALDH1A1TDP1L3MBTL1FOLH1RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6686106-B2 POLYIMIDESILOXANE COPOLYMERS UBE INDUSTRIES, LTD. (JP) 2004-02-03 US disclosed
US-20020001763-A1 Photosensitive resin compositions, insulating films, and processes for formation of the films UBE INDUSTRIES, LTD. 2002-01-03 US disclosed