Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 6/20 | 0.62 |
| ▸ | NPC1 | O15118 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.55 |
| ▸ | KDM1A | O60341 | 2/20 | 0.54 |
| ▸ | MAOA | P21397 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | FPR2 | P25090 | 1/20 | 0.54 |
| ▸ | MGLL | Q99685 | 1/20 | 0.53 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.53 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1223807 | 0.96 | RAB9A (0.67) | MAPTTP53RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11813314 | 0.90 | TP53 (0.68) | MAPTTP53RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6743382 | 0.85 | NAMPT (0.61) | MAPTALDH1A1POLBLMNAGAA | |
| SCHEMBL3034797 | 0.84 | MIF (0.60) | MAPTTP53RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6738542 | 0.84 | TP53 (0.54) | MAPTTP53RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL31043751 | 0.83 | AR (0.60) | MAPTTP53RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4333325 | 0.82 | FPR2 (0.54) | MAPTTP53RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28246624 | 0.82 | NPC1 (0.68) | MAPTTP53RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9800498 | 0.82 | FPR2 (0.65) | MAPTRAB9ASMN1; SMN2ALDH1A1ATM | |
| Benzyl Phenylcarbamate SCHEMBL1222943 | 0.82 | POLB (0.78) | MAPTTP53RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040063783-A1 | Nitroso diphenylamine derivatives | MERCK PATENT GMBH (DE) | 2004-04-01 | — | — | US | disclosed |
| EP-1322598-A1 | NITROSO DIPHENYLAMINE DERIVATIVES | MERCK PATENT GmbH (DE) | 2003-07-02 | — | — | EP | disclosed |
| WO-2002028820-A1 | NITROSO DIPHENYLAMINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2002-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063783-A1 | Nitroso diphenylamine derivatives | NQO2, SULT1A1, NAT1 | MAPT 1547/4885TP53 1326/4885RAB9A 1977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.