SCHEMBL674341

SCHEMBL674341

C/C(=C/C(C)(CC(C)(C)c1cc(C)c(O)c(C)c1)c1cc(C)c(O)c(C)c1)c1cc(C)c(O)c(C)c1

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
ALOX5 P09917 1/20 0.36
PTGS1 P23219 1/20 0.36
PTGS2 P35354 1/20 0.36
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL674342 1.00 ESR1 (0.37) ESR1ESR2ALOX5PTGS1PTGS2
SCHEMBL674803 0.77 ESR1 (0.44) ESR1ESR2PTGS1PTGS2
SCHEMBL674804 0.77 ESR1 (0.44) ESR1ESR2PTGS1PTGS2
SCHEMBL674805 0.77 ESR1 (0.44) ESR1ESR2PTGS1PTGS2
SCHEMBL11144148 0.76 PTGS1 (0.41) ESR1ESR2ALOX5PTGS1PTGS2
SCHEMBL11144151 0.76 PTGS1 (0.41) ESR1ESR2ALOX5PTGS1PTGS2
SCHEMBL200257 0.72 SHBG (0.54) ESR1ESR2ALOX5PTGS1PTGS2
SCHEMBL247685 0.70 SHBG (0.53) ESR1ESR2PTGS1PTGS2
SCHEMBL18600 0.70 SHBG (0.53) ESR1ESR2PTGS1PTGS2
Phloroglucinol SCHEMBL28432567 0.70 SHBG (0.49) ESR1ESR2PTGS1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1966279-A1 POLYFUNCTIONAL POLY(ARYLENE ETHER) METHOD General Electric Company (US) 2008-09-10 EP claimed
WO-2007058779-A1 POLYFUNCTIONAL POLY(ARYLENE ETHER) METHOD GENERAL ELECTRIC COMPANY (US) 2007-05-24 WO claimed
US-20070106051-A1 Polyfunctional poly(arylene ether) method CITIBANK, N.A., AS COLLATERAL AGENT 2007-05-10 US claimed
EP-2867275-B1 POLY(PHENYLENE ETHER) PROCESS SABIC GLOBAL TECHNOLOGIES BV (NL) 2017-11-22 EP disclosed
EP-2867275-A1 POLY(PHENYLENE ETHER) PROCESS SABIC Innovative Plastics IP B.V. (NL) 2015-05-06 EP disclosed
US-8734693-B2 Method of separating a poly(arylene ether) composition from a solvent, and poly(arylene ether) composition prepared thereby SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-05-27 US disclosed
WO-2014003819-A1 POLY(PHENYLENE ETHER) PROCESS SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-01-03 WO disclosed
US-8466253-B1 Poly(phenylene ether) process SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2013-06-18 US disclosed
US-20120277399-A1 METHOD OF SEPARATING A POLY(ARYLENE ETHER) COMPOSITION FROM A SOLVENT, AND POLY(ARYLENE ETHER) COMPOSITION PREPARED THEREBY SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2012-11-01 US disclosed
US-8075812-B2 Method of separating a poly(arylene ether) composition from a solvent, and poly(arylene ether) composition prepared thereby SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-12-13 US disclosed
US-8058359-B2 Varnish compositions for electrical insulation and method of using the same SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-11-15 US disclosed
WO-2008124488-A1 METHOD OF SEPARATING A POLY(ARYLENE ETHER) COMPOSITION FROM A SOLVENT, AND POLY(ARYLENE ETHER) COMPOSITION PREPARED THEREBY SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-10-16 WO disclosed
US-20080246173-A1 METHOD OF SEPARATING A POLY(ARYLENE ETHER) COMPOSITION FROM A SOLVENT, AND POLY(ARYLENE ETHER) COMPOSITION PREPARED THEREBY SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2008-10-09 US disclosed
EP-1966279-A1 POLYFUNCTIONAL POLY(ARYLENE ETHER) METHOD General Electric Company (US) 2008-09-10 EP disclosed
WO-2008094796-A1 COMPOSITE-FORMING METHOD, COMPOSITES FORMED THEREBY, AND PRINTED CIRCUIT BOARDS INCORPORATING THEM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-08-07 WO disclosed
US-20080178983-A1 COMPOSITE-FORMING METHOD, COMPOSITES FORMED THEREBY, AND PRINTED CIRCUIT BOARDS INCORPORATING THEM SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2008-07-31 US disclosed
US-20080097069-A1 POLY(ARYLENE ETHER) METHOD AND COMPOSITION CITIBANK, N.A., AS COLLATERAL AGENT 2008-04-24 US disclosed
WO-2008048735-A1 POLY (ARYLENE ETHER) AND METHOD FOR PREPARING THEM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-04-24 WO disclosed
WO-2007058779-A1 POLYFUNCTIONAL POLY(ARYLENE ETHER) METHOD GENERAL ELECTRIC COMPANY (US) 2007-05-24 WO disclosed
US-20070106051-A1 Polyfunctional poly(arylene ether) method CITIBANK, N.A., AS COLLATERAL AGENT 2007-05-10 US disclosed