Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 17/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.41 |
| ▸ | AR | P10275 | 4/20 | 0.41 |
| ▸ | ESRRG | P62508 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL674804 | 1.00 | ESR1 (0.44) | ESR1ESR2ARESRRGPTGS2 | |
| SCHEMBL674805 | 1.00 | ESR1 (0.44) | ESR1ESR2ARESRRGPTGS2 | |
| SCHEMBL674341 | 0.77 | ESR1 (0.37) | ESR1ESR2PTGS2PTGS1 | |
| SCHEMBL674342 | 0.77 | ESR1 (0.37) | ESR1ESR2PTGS2PTGS1 | |
| SCHEMBL11336835 | 0.75 | ESRRG (0.36) | ESR1ESR2ESRRGPTGS2CYP3A4 | |
| SCHEMBL11336839 | 0.75 | ESRRG (0.36) | ESR1ESR2ESRRGPTGS2CYP3A4 | |
| SCHEMBL247685 | 0.75 | SHBG (0.53) | ESR1ESR2ARESRRGPTGS2 | |
| SCHEMBL18600 | 0.75 | SHBG (0.53) | ESR1ESR2ARESRRGPTGS2 | |
| Phloroglucinol SCHEMBL28432567 | 0.74 | SHBG (0.49) | ESR1ESR2ARESRRGPTGS2 | |
| SCHEMBL9355691 | 0.73 | ESR1 (0.61) | ESR1ESR2ARCYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966279-A1 | POLYFUNCTIONAL POLY(ARYLENE ETHER) METHOD | General Electric Company (US) | 2008-09-10 | — | — | EP | claimed |
| WO-2007058779-A1 | POLYFUNCTIONAL POLY(ARYLENE ETHER) METHOD | GENERAL ELECTRIC COMPANY (US) | 2007-05-24 | — | — | WO | claimed |
| US-20070106051-A1 | Polyfunctional poly(arylene ether) method | CITIBANK, N.A., AS COLLATERAL AGENT | 2007-05-10 | — | — | US | claimed |
| EP-2867275-B1 | POLY(PHENYLENE ETHER) PROCESS | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2017-11-22 | — | — | EP | disclosed |
| EP-2867275-A1 | POLY(PHENYLENE ETHER) PROCESS | SABIC Innovative Plastics IP B.V. (NL) | 2015-05-06 | — | — | EP | disclosed |
| US-8734693-B2 | Method of separating a poly(arylene ether) composition from a solvent, and poly(arylene ether) composition prepared thereby | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2014-05-27 | — | — | US | disclosed |
| WO-2014003819-A1 | POLY(PHENYLENE ETHER) PROCESS | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2014-01-03 | — | — | WO | disclosed |
| US-8466253-B1 | Poly(phenylene ether) process | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2013-06-18 | — | — | US | disclosed |
| US-20120277399-A1 | METHOD OF SEPARATING A POLY(ARYLENE ETHER) COMPOSITION FROM A SOLVENT, AND POLY(ARYLENE ETHER) COMPOSITION PREPARED THEREBY | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2012-11-01 | — | — | US | disclosed |
| US-8075812-B2 | Method of separating a poly(arylene ether) composition from a solvent, and poly(arylene ether) composition prepared thereby | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2011-12-13 | — | — | US | disclosed |
| US-8058359-B2 | Varnish compositions for electrical insulation and method of using the same | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2011-11-15 | — | — | US | disclosed |
| WO-2008124488-A1 | METHOD OF SEPARATING A POLY(ARYLENE ETHER) COMPOSITION FROM A SOLVENT, AND POLY(ARYLENE ETHER) COMPOSITION PREPARED THEREBY | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2008-10-16 | — | — | WO | disclosed |
| US-20080246173-A1 | METHOD OF SEPARATING A POLY(ARYLENE ETHER) COMPOSITION FROM A SOLVENT, AND POLY(ARYLENE ETHER) COMPOSITION PREPARED THEREBY | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2008-10-09 | — | — | US | disclosed |
| EP-1966279-A1 | POLYFUNCTIONAL POLY(ARYLENE ETHER) METHOD | General Electric Company (US) | 2008-09-10 | — | — | EP | disclosed |
| WO-2008094796-A1 | COMPOSITE-FORMING METHOD, COMPOSITES FORMED THEREBY, AND PRINTED CIRCUIT BOARDS INCORPORATING THEM | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2008-08-07 | — | — | WO | disclosed |
| US-20080178983-A1 | COMPOSITE-FORMING METHOD, COMPOSITES FORMED THEREBY, AND PRINTED CIRCUIT BOARDS INCORPORATING THEM | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2008-07-31 | — | — | US | disclosed |
| US-20080097069-A1 | POLY(ARYLENE ETHER) METHOD AND COMPOSITION | CITIBANK, N.A., AS COLLATERAL AGENT | 2008-04-24 | — | — | US | disclosed |
| WO-2008048735-A1 | POLY (ARYLENE ETHER) AND METHOD FOR PREPARING THEM | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2008-04-24 | — | — | WO | disclosed |
| WO-2007058779-A1 | POLYFUNCTIONAL POLY(ARYLENE ETHER) METHOD | GENERAL ELECTRIC COMPANY (US) | 2007-05-24 | — | — | WO | disclosed |
| US-20070106051-A1 | Polyfunctional poly(arylene ether) method | CITIBANK, N.A., AS COLLATERAL AGENT | 2007-05-10 | — | — | US | disclosed |