SCHEMBL674805

SCHEMBL674805

CC(=CC(C)(CC(C)(C)c1ccc(O)c(C)c1)c1ccc(O)c(C)c1)c1ccc(O)c(C)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 17/20 0.44
ESR2 Q92731 7/20 0.41
AR P10275 4/20 0.41
ESRRG P62508 1/20 0.39
PTGS2 P35354 1/20 0.36
CYP3A4 P08684 2/20 0.35
CYP2D6 P10635 1/20 0.35
HIF1A Q16665 1/20 0.35
MEN1 O00255 1/20 0.33
USP2 O75604 1/20 0.33
TP53 P04637 1/20 0.33
PGR P06401 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
MAPT P10636 1/20 0.33
DRD1 P21728 1/20 0.33
PTGS1 P23219 1/20 0.33
SLC6A2 P23975 1/20 0.33
PDE4A P27815 1/20 0.33
MAPK1 P28482 1/20 0.33
CASP1 P29466 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL674803 1.00 ESR1 (0.44) ESR1ESR2ARESRRGPTGS2
SCHEMBL674804 1.00 ESR1 (0.44) ESR1ESR2ARESRRGPTGS2
SCHEMBL674341 0.77 ESR1 (0.37) ESR1ESR2PTGS2PTGS1
SCHEMBL674342 0.77 ESR1 (0.37) ESR1ESR2PTGS2PTGS1
SCHEMBL11336835 0.75 ESRRG (0.36) ESR1ESR2ESRRGPTGS2CYP3A4
SCHEMBL11336839 0.75 ESRRG (0.36) ESR1ESR2ESRRGPTGS2CYP3A4
SCHEMBL247685 0.75 SHBG (0.53) ESR1ESR2ARESRRGPTGS2
SCHEMBL18600 0.75 SHBG (0.53) ESR1ESR2ARESRRGPTGS2
Phloroglucinol SCHEMBL28432567 0.74 SHBG (0.49) ESR1ESR2ARESRRGPTGS2
SCHEMBL9355691 0.73 ESR1 (0.61) ESR1ESR2ARCYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1966279-A1 POLYFUNCTIONAL POLY(ARYLENE ETHER) METHOD General Electric Company (US) 2008-09-10 EP claimed
WO-2007058779-A1 POLYFUNCTIONAL POLY(ARYLENE ETHER) METHOD GENERAL ELECTRIC COMPANY (US) 2007-05-24 WO claimed
US-20070106051-A1 Polyfunctional poly(arylene ether) method CITIBANK, N.A., AS COLLATERAL AGENT 2007-05-10 US claimed
EP-2867275-B1 POLY(PHENYLENE ETHER) PROCESS SABIC GLOBAL TECHNOLOGIES BV (NL) 2017-11-22 EP disclosed
EP-2867275-A1 POLY(PHENYLENE ETHER) PROCESS SABIC Innovative Plastics IP B.V. (NL) 2015-05-06 EP disclosed
US-8734693-B2 Method of separating a poly(arylene ether) composition from a solvent, and poly(arylene ether) composition prepared thereby SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-05-27 US disclosed
WO-2014003819-A1 POLY(PHENYLENE ETHER) PROCESS SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-01-03 WO disclosed
US-8466253-B1 Poly(phenylene ether) process SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2013-06-18 US disclosed
US-20120277399-A1 METHOD OF SEPARATING A POLY(ARYLENE ETHER) COMPOSITION FROM A SOLVENT, AND POLY(ARYLENE ETHER) COMPOSITION PREPARED THEREBY SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2012-11-01 US disclosed
US-8075812-B2 Method of separating a poly(arylene ether) composition from a solvent, and poly(arylene ether) composition prepared thereby SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-12-13 US disclosed
US-8058359-B2 Varnish compositions for electrical insulation and method of using the same SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-11-15 US disclosed
WO-2008124488-A1 METHOD OF SEPARATING A POLY(ARYLENE ETHER) COMPOSITION FROM A SOLVENT, AND POLY(ARYLENE ETHER) COMPOSITION PREPARED THEREBY SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-10-16 WO disclosed
US-20080246173-A1 METHOD OF SEPARATING A POLY(ARYLENE ETHER) COMPOSITION FROM A SOLVENT, AND POLY(ARYLENE ETHER) COMPOSITION PREPARED THEREBY SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2008-10-09 US disclosed
EP-1966279-A1 POLYFUNCTIONAL POLY(ARYLENE ETHER) METHOD General Electric Company (US) 2008-09-10 EP disclosed
WO-2008094796-A1 COMPOSITE-FORMING METHOD, COMPOSITES FORMED THEREBY, AND PRINTED CIRCUIT BOARDS INCORPORATING THEM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-08-07 WO disclosed
US-20080178983-A1 COMPOSITE-FORMING METHOD, COMPOSITES FORMED THEREBY, AND PRINTED CIRCUIT BOARDS INCORPORATING THEM SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2008-07-31 US disclosed
US-20080097069-A1 POLY(ARYLENE ETHER) METHOD AND COMPOSITION CITIBANK, N.A., AS COLLATERAL AGENT 2008-04-24 US disclosed
WO-2008048735-A1 POLY (ARYLENE ETHER) AND METHOD FOR PREPARING THEM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-04-24 WO disclosed
WO-2007058779-A1 POLYFUNCTIONAL POLY(ARYLENE ETHER) METHOD GENERAL ELECTRIC COMPANY (US) 2007-05-24 WO disclosed
US-20070106051-A1 Polyfunctional poly(arylene ether) method CITIBANK, N.A., AS COLLATERAL AGENT 2007-05-10 US disclosed