Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8582933 | 0.77 | — | — | |
| SCHEMBL14800640 | 0.76 | ALDH1A1 (0.46) | GRM4ALDH1A1TDP1PLA2G7NPC1 | |
| SCHEMBL1369210 | 0.72 | ALDH1A1 (0.50) | GRM4ALDH1A1TDP1PLA2G7NPC1 | |
| SCHEMBL7254231 | 0.71 | ALDH1A1 (0.47) | GRM4ALDH1A1TDP1PLA2G7NPC1 | |
| SCHEMBL10749872 | 0.70 | SMN1; SMN2 (0.37) | NPC1RAB9AGAAHPGDSMN1; SMN2 | |
| SCHEMBL70760 | 0.68 | HSD17B10 (0.44) | GRM4ALDH1A1TDP1NPC1RAB9A | |
| SCHEMBL722560 | 0.68 | RAB9A (0.59) | ALDH1A1TDP1PLA2G7NPC1RAB9A | |
| SCHEMBL2546678 | 0.67 | GRM4 (0.47) | GRM4ALDH1A1TDP1PLA2G7NPC1 | |
| Hydrochloric Acid SCHEMBL6833454 | 0.67 | RAB9A (0.57) | ALDH1A1TDP1PLA2G7NPC1RAB9A | |
| Bromide SCHEMBL7502411 | 0.67 | RAB9A (0.57) | ALDH1A1TDP1PLA2G7NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040023979-A1 | Process for making substituted thiazolyl-amino pyridines | ZHAO MATTHEW M (US) | 2004-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040023979-A1 | Process for making substituted thiazolyl-amino pyridines | ERBB2, ERBB4, TYRO3 | GRM4 753/4885ALDH1A1 3570/4885TDP1 3200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.