Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | SDHB | P21912 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 5/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.31 |
| ▸ | STAT3 | P40763 | 4/20 | 0.31 |
| ▸ | TP53 | P04637 | 3/20 | 0.31 |
| ▸ | HTT | P42858 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9329671 | 0.90 | LMNA (0.60) | LMNASMN1; SMN2KMT2AKDM4EALDH1A1 | |
| SCHEMBL9432915 | 0.83 | LMNA (0.73) | LMNASMN1; SMN2KMT2AKDM4EALDH1A1 | |
| SCHEMBL6561352 | 0.79 | SMN1; SMN2 (0.78) | LMNASMN1; SMN2KMT2AKDM4EALDH1A1 | |
| SCHEMBL1051087 | 0.75 | LMNA (0.52) | LMNASMN1; SMN2KMT2AKDM4EALDH1A1 | |
| SCHEMBL8869963 | 0.75 | LMNA (0.50) | LMNASMN1; SMN2KMT2AKDM4EALDH1A1 | |
| SCHEMBL13012208 | 0.74 | KMT2A (0.42) | LMNASMN1; SMN2KMT2AALDH1A1GAA | |
| SCHEMBL27836920 | 0.73 | KMT2A (0.41) | LMNASMN1; SMN2KMT2AKDM4EALDH1A1 | |
| SCHEMBL9902644 | 0.73 | LMNA (0.62) | LMNASMN1; SMN2KMT2AKDM4EALDH1A1 | |
| SCHEMBL8629598 | 0.72 | CYP1A2 (0.50) | SMN1; SMN2GAARAB9ACYP1A2CYP2C19 | |
| SCHEMBL9432361 | 0.72 | ALDH1A1 (0.49) | LMNASMN1; SMN2KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040023805-A1 | Substituted phenyluracils | ANDREE ROLAND (DE) | 2004-02-05 | — | — | US | disclosed |
| US-6649760-B2 | Herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2003-11-18 | — | — | US | disclosed |
| CN-1420873-A | Substituted phenyluracils | BAYER AG (DE) | 2003-05-28 | — | — | CN | disclosed |
| EP-1272478-A1 | SUBSTITUTED PHENYLURACILS | Bayer Aktiengesellschaft (DE) | 2003-01-08 | — | — | EP | disclosed |
| US-20020173425-A1 | Substituted phenyluracils | BAYER AKTIENGESELLSCHAFT (DE) | 2002-11-21 | — | — | US | disclosed |
| WO-2001077084-A1 | SUBSTITUTED PHENYLURACILS | BAYER CROPSCIENCE AG (DE) | 2001-10-18 | — | — | WO | disclosed |
| US-5284820-A | Herbicidal substituted cycloalkenes | BAYER AKTIENGESELLSCHAFT (DE) | 1994-02-08 | — | — | US | disclosed |
| EP-0532948-A1 | Substituted cycloalkenes as herbicides | BAYER AG (DE) | 1993-03-24 | — | — | EP | disclosed |
| EP-0158594-B1 | PROCESS FOR THE PREPARATION OF FLUOROALKOXY-AMINO-PYRIMIDINES | CIBA-GEIGY AG (CH) | 1988-02-10 | — | — | EP | disclosed |
| EP-0158594-A1 | Process for the preparation of fluoroalkoxy-amino-pyrimidines | CIBA-GEIGY AG (CH) | 1985-10-16 | — | — | EP | disclosed |
| US-4542216-A | FLUOROALKYLATION OF A THIOPYRAMIDINE | CIBA GEIGY CORPORATION (US) | 1985-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020173425-A1 | Substituted phenyluracils | DPYD, POP1, G6PD | LMNA 4406/4885SMN1; SMN2 3026/4885KMT2A 1862/4885 |
| US-20040023805-A1 | Substituted phenyluracils | DPYD, POP1, G6PD | LMNA 4406/4885SMN1; SMN2 3026/4885KMT2A 1862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.