Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.34 |
| ▸ | HPGD | P15428 | 6/20 | 0.34 |
| ▸ | SDHB | P21912 | 6/20 | 0.34 |
| ▸ | TP53 | P04637 | 5/20 | 0.34 |
| ▸ | HTT | P42858 | 5/20 | 0.34 |
| ▸ | STAT3 | P40763 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.34 |
| ▸ | STAT1 | P42224 | 2/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9432915 | 0.93 | LMNA (0.73) | LMNASMN1; SMN2KMT2AKDM4EALDH1A1 | |
| SCHEMBL6744329 | 0.90 | LMNA (0.49) | LMNASMN1; SMN2KMT2AKDM4EALDH1A1 | |
| SCHEMBL9902644 | 0.82 | LMNA (0.62) | LMNASMN1; SMN2KMT2AKDM4EALDH1A1 | |
| SCHEMBL27836920 | 0.79 | KMT2A (0.41) | LMNASMN1; SMN2KMT2AKDM4EALDH1A1 | |
| SCHEMBL9903569 | 0.77 | SMN1; SMN2 (0.55) | LMNASMN1; SMN2KMT2AKDM4EALDH1A1 | |
| SCHEMBL1067726 | 0.75 | SMN1; SMN2 (1.00) | LMNASMN1; SMN2KMT2AKDM4EALDH1A1 | |
| SCHEMBL38662046 | 0.73 | LMNA (0.60) | LMNASMN1; SMN2KMT2AKDM4EALDH1A1 | |
| SCHEMBL13012204 | 0.73 | PDE2A (0.35) | KMT2A | |
| SCHEMBL8953787 | 0.71 | SMN1; SMN2 (0.62) | LMNASMN1; SMN2KMT2AKDM4EALDH1A1 | |
| SCHEMBL4433293 | 0.71 | LMNA (0.74) | LMNASMN1; SMN2KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4731623-A1 | CARBOLINE COMPOUNDS AND USE THEREOF | PTC Therapeutics, Inc. (US) | 2026-04-29 | — | — | EP | disclosed |
| WO-2025006078-A1 | CARBOLINE COMPOUNDS AND USE THEREOF | PTC THERAPEUTICS, INC. (US) | 2025-01-02 | — | — | WO | disclosed |
| EP-0375617-B1 | Process for the preparation of pyrimidine derivatives | CIBA GEIGY AG (CH) | 1994-04-06 | — | — | EP | disclosed |
| US-5284820-A | Herbicidal substituted cycloalkenes | BAYER AKTIENGESELLSCHAFT (DE) | 1994-02-08 | — | — | US | disclosed |
| EP-0355385-B1 | SUBSTITUTED 4-SULPHONYLAMINO-2-AZINYL-1,2,4-TRIAZOL-3-ONES, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | BAYER AG (DE) | 1993-05-19 | — | — | EP | disclosed |
| EP-0532948-A1 | Substituted cycloalkenes as herbicides | BAYER AG (DE) | 1993-03-24 | — | — | EP | disclosed |
| US-5151514-A | Triazine substituted herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1992-09-29 | — | — | US | disclosed |
| US-5142060-A | Herbicidal substituted 4-sulphonylamino-2-azinyl-1,2,4-triazol-3-ones | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-25 | — | — | US | disclosed |
| US-5089627-A | Chemical intermediates therefor | BAYER AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |
| US-5085687-A | HERBICIDAL SUBSTITUTED 4-SULPHONYLAMINO-2-AZINYL-1,2,4-TRIAZOL-3-ONES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-02-04 | — | — | US | disclosed |
| US-4988381-A | HERBICIDES, PLANT GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-29 | — | — | US | disclosed |
| EP-0375617-A1 | Process for the preparation of pyrimidine derivatives | CIBA-GEIGY AG (CH) | 1990-06-27 | — | — | EP | disclosed |
| EP-0355385-A1 | Substituted 4-sulphonylamino-2-azinyl-1,2,4-triazol-3-ones, process and intermediates for their preparation and their use as herbicides | BAYER AG (DE) | 1990-02-28 | — | — | EP | disclosed |
| US-4900827-A | Process for the preparation of pyrimidine derivatives | CIBA-GEIGY CORPORATION (US) | 1990-02-13 | — | — | US | disclosed |
| EP-0158594-B1 | PROCESS FOR THE PREPARATION OF FLUOROALKOXY-AMINO-PYRIMIDINES | CIBA-GEIGY AG (CH) | 1988-02-10 | — | — | EP | disclosed |
| EP-0158594-A1 | Process for the preparation of fluoroalkoxy-amino-pyrimidines | CIBA-GEIGY AG (CH) | 1985-10-16 | — | — | EP | disclosed |
| US-4542216-A | FLUOROALKYLATION OF A THIOPYRAMIDINE | CIBA GEIGY CORPORATION (US) | 1985-09-17 | — | — | US | disclosed |