Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CD69 | Q07108 | 3/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ACLY | P53396 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7390249 | 0.87 | SCN5A (0.54) | SMN1; SMN2NPC1RAB9AKMT2ACD69 | |
| SCHEMBL14060872 | 0.87 | L3MBTL1 (0.47) | SMN1; SMN2KMT2ACD69TSHRPOLB | |
| SCHEMBL7288512 | 0.82 | L3MBTL1 (0.50) | SMN1; SMN2KMT2AMCL1TSHRHTT | |
| SCHEMBL830740 | 0.82 | KMT2A (0.60) | SMN1; SMN2NPC1RAB9AKMT2ACD69 | |
| SCHEMBL7390982 | 0.80 | KMT2A (0.44) | SMN1; SMN2NPC1RAB9AKMT2ATSHR | |
| SCHEMBL14042532 | 0.79 | PTGDR2 (0.45) | SMN1; SMN2KMT2ACD69MCL1ALDH1A1 | |
| SCHEMBL14750655 | 0.79 | CD69 (0.46) | SMN1; SMN2KMT2ACD69MCL1HTT | |
| SCHEMBL16784835 | 0.77 | SMN1; SMN2 (0.53) | SMN1; SMN2KMT2ATSHRALDH1A1ALOX15 | |
| SCHEMBL10459386 | 0.76 | L3MBTL1 (0.47) | SMN1; SMN2KMT2AMCL1TSHRHTT | |
| SCHEMBL28044483 | 0.76 | KMT2A (0.53) | SMN1; SMN2NPC1RAB9AKMT2ACD69 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696494-B2 | HUMAN IMMUNODEFICIENCY VIRUS | ENANTA PHARMACEUTICALS, INC. | 2004-02-24 | — | — | US | disclosed |
| US-20030207934-A1 | Alpha-hydroxyarylbutanamine inhibitors of aspartyl protease | ENANTA PHARMACEUTICALS, INC. | 2003-11-06 | — | — | US | disclosed |
| WO-2003034989-A2 | α-HYDROXYARYLBUTANAMINE INHIBITORS OF ASPARTYL PROTEASE | ENANTA PHARMACEUTICALS, INC. (US) | 2003-05-01 | — | — | WO | disclosed |
| EP-0413839-A1 | GHRH analogs | The Administrators of The Tulane Educational Fund (US) | 1991-02-27 | — | — | EP | disclosed |
| US-4914189-A | STIMULATES RELEASE OF GROWTH HORMONE | THE ADMINSTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 1990-04-03 | — | — | US | disclosed |
| EP-0277626-A2 | Synthetic GHRH analogs | The Administrators of The Tulane Educational Fund (US) | 1988-08-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030207934-A1 | Alpha-hydroxyarylbutanamine inhibitors of aspartyl protease | DNPEP, ASPH, CTSC | SMN1; SMN2 3669/4885NPC1 411/4885RAB9A 2541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.