Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.54 |
| ▸ | THRA | P10827 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CD69 | Q07108 | 3/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | ACLY | P53396 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6744370 | 0.87 | SMN1; SMN2 (0.51) | KMT2ACD69MCL1ACLYSMN1; SMN2 | |
| SCHEMBL14750655 | 0.86 | CD69 (0.46) | SCN5ATHRATHRBKMT2ACD69 | |
| SCHEMBL14060872 | 0.82 | L3MBTL1 (0.47) | KMT2ACD69SMN1; SMN2POLBGLA | |
| SCHEMBL7391291 | 0.81 | SCN5A (0.50) | SCN5AKMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL830740 | 0.77 | KMT2A (0.60) | KMT2ACD69SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7390982 | 0.76 | KMT2A (0.44) | KMT2AACLYSMN1; SMN2NPC1RAB9A | |
| SCHEMBL14042532 | 0.75 | PTGDR2 (0.45) | THRATHRBKMT2ACD69MCL1 | |
| SCHEMBL7288512 | 0.74 | L3MBTL1 (0.50) | KMT2AMCL1SMN1; SMN2POLBGLA | |
| SCHEMBL16621892 | 0.73 | THRB (0.50) | THRATHRBKMT2ACD69GLA | |
| SCHEMBL16784835 | 0.72 | SMN1; SMN2 (0.53) | KMT2ASMN1; SMN2ALOX15POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5905068-A | Retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 1999-05-18 | — | — | US | disclosed |