SCHEMBL6744610

SCHEMBL6744610

O=Cc1cc(O)c(O)c(-c2ccccc2)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 3/20 0.49
PTPN6 P29350 1/20 0.49
BACE1 P56817 1/20 0.48
EGFR P00533 1/20 0.44
KDM4E B2RXH2 1/20 0.44
PTGS2 P35354 1/20 0.44
RAB9A P51151 1/20 0.44
PELI1 Q96FA3 1/20 0.44
XDH P47989 1/20 0.43
ALOX5 P09917 1/20 0.42
ALDH1A1 P00352 2/20 0.42
HPGD P15428 1/20 0.42
BCL2L1 Q07817 1/20 0.42
HSD17B10 Q99714 1/20 0.42
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
CYP2A6 P11509 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC8 Q9BY41 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9472211 0.90 PTPN1 (0.53) PTPN1PTPN6BACE1EGFRPELI1
Benzaldehyde SCHEMBL28979739 0.82 BACE1 (0.50) PTPN1PTPN6BACE1EGFRPELI1
SCHEMBL3933848 0.81 KDM4E (0.57) BACE1EGFRKDM4EPTGS2RAB9A
SCHEMBL18218312 0.81 PTPN1 (0.45) PTPN1PTPN6BACE1EGFRKDM4E
SCHEMBL5460091 0.81 PTPN1 (0.74) PTPN1PTPN6EGFRHPGDHSD17B10
Benzaldehyde SCHEMBL17963717 0.80 ALDH1A1 (0.61) KDM4EPTGS2RAB9AXDHALDH1A1
SCHEMBL9763217 0.79 PELI1 (0.62) PTPN1PTPN6BACE1KDM4EPTGS2
SCHEMBL31194720 0.79 PELI1 (0.62) PTPN1PTPN6BACE1KDM4EPTGS2
SCHEMBL2649406 0.78 ERN1 (0.51) BACE1PTGS2ALOX5ALDH1A1HPGD
SCHEMBL132439 0.75 XDH (0.59) EGFRKDM4EPTGS2RAB9AXDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6693062-B2 LIGHT INSENSITIVE ORGANIC SILVER SALTS, REDUCING AGENTS AND 1,2-DIHYDROXYBENZENE DERIVATIVE AGFA-GEVAERT (BE) 2004-02-17 US disclosed