Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | BACE1 | P56817 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.47 |
| ▸ | PELI1 | Q96FA3 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.43 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.43 |
| ▸ | ALDH5A1 | P51649 | 3/20 | 0.43 |
| ▸ | ABAT | P80404 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9763217 | 0.86 | PELI1 (0.62) | KDM4EPTGS2RAB9AALOX5BACE1 | |
| SCHEMBL31194720 | 0.86 | PELI1 (0.62) | KDM4EPTGS2RAB9AALOX5BACE1 | |
| SCHEMBL35967 | 0.83 | ALDH1A1 (0.48) | KDM4EPTGS2RAB9AALOX5BACE1 | |
| SCHEMBL25068953 | 0.83 | ADORA3 (0.51) | KDM4EPTGS2RAB9AALOX5BACE1 | |
| SCHEMBL6744610 | 0.81 | PTPN1 (0.49) | KDM4EPTGS2RAB9AALOX5BACE1 | |
| SCHEMBL29818628 | 0.80 | ALDH1A1 (0.46) | KDM4EPTGS2RAB9ABACE1ALDH1A1 | |
| SCHEMBL5490742 | 0.80 | ALDH1A1 (0.50) | KDM4EALDH1A1PELI1CYP2A6TRIM24 | |
| SCHEMBL29671482 | 0.80 | ALDH1A1 (0.50) | KDM4EALDH1A1PELI1CYP2A6TRIM24 | |
| SCHEMBL17422065 | 0.80 | ALDH1A1 (0.46) | KDM4EPTGS2RAB9ABACE1ALDH1A1 | |
| 2-Phenylphenol SCHEMBL28116733 | 0.80 | ALDH1A1 (0.68) | ALOX5BACE1ALDH1A1HPGDBCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116621878-A | Phosphor, long-life room-temperature phosphorescent material for light-driven phosphorescent growth and application | 重庆理工大学 | 2023-08-22 | — | — | CN | claimed |
| CN-113621137-B | Preparation method of cyclophosphazenitrile polyimine vitrimer and application of same in preparation of epoxy resin and polyurethane material | 北京化工大学 | 2022-10-18 | — | — | CN | claimed |
| CN-1646478-A | 3-aminophenol derivatives substituted in the 2-position and colorants comprising the same | P & G CLAIROL INC (US) | 2005-07-27 | — | — | CN | claimed |
| CN-118978924-A | Polymerizable self-assembled vertical orientation layer and preparation method and application thereof | 北京科技大学 | 2024-11-19 | — | — | CN | disclosed |
| CN-113754589-B | Compositions, methods, and systems for synthesizing and using contrast agents | 蓝瑟斯医学影像公司 | 2024-09-27 | — | — | CN | disclosed |
| CN-116621878-A | Phosphor, long-life room-temperature phosphorescent material for light-driven phosphorescent growth and application | 重庆理工大学 | 2023-08-22 | — | — | CN | disclosed |
| CN-113621137-B | Preparation method of cyclophosphazenitrile polyimine vitrimer and application of same in preparation of epoxy resin and polyurethane material | 北京化工大学 | 2022-10-18 | — | — | CN | disclosed |
| CN-111094300-B | Benzo-heteroaryl derivative, preparation method and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2022-09-16 | — | — | CN | disclosed |
| CN-104059082-A | Nitroimidazole heterocyclic compound and application of nitroimidazole heterocyclic compound in preparation of medicine for treating tuberculosis | METABOMICS INC | 2014-09-24 | — | — | CN | disclosed |
| EP-1698635-B1 | BENZIMIDAZOLE DERIVATIVES AND MEDICAL USES THEREOF | KISSEI PHARMACEUTICAL (JP) | 2011-12-14 | — | — | EP | disclosed |
| US-7547680-B2 | Benzimidazole derivatives and medical uses thereof | KISSEI PHARMACEUTICALS, CO., LTD. (JP) | 2009-06-16 | — | — | US | disclosed |
| US-20080038242-A1 | Benzimidazole derivatives and medical uses thereof | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2008-02-14 | — | — | US | disclosed |
| EP-1698635-A1 | BENZIMIDAZOLE DERIVATIVES AND MEDICAL USES THEREOF | Kissei Pharmaceutical Co., Ltd. (JP) | 2006-09-06 | — | — | EP | disclosed |
| CN-1784379-A | Hydroxy-biphenyl-carbaldehyde oxime derivatives and their use as estrogenic agents | WYETH CORP (US) | 2006-06-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080038242-A1 | Benzimidazole derivatives and medical uses thereof | SLCO1B3, SLCO2A1, SLCO2B1 | KDM4E 2804/4885PTGS2 2556/4885RAB9A 3021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.