Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PELI1 | Q96FA3 | 4/20 | 0.62 |
| ▸ | BACE1 | P56817 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ALDH5A1 | P51649 | 2/20 | 0.46 |
| ▸ | ABAT | P80404 | 2/20 | 0.46 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.46 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31194720 | 1.00 | PELI1 (0.62) | PELI1BACE1KDM4EPTGS2RAB9A | |
| SCHEMBL12005282 | 0.87 | PELI1 (0.53) | PELI1BACE1KDM4EPTGS2RAB9A | |
| SCHEMBL3933848 | 0.86 | KDM4E (0.57) | PELI1BACE1KDM4EPTGS2RAB9A | |
| SCHEMBL14136887 | 0.82 | ALDH1A1 (0.58) | PELI1KDM4EPTGS2RAB9AALDH1A1 | |
| SCHEMBL35967 | 0.82 | ALDH1A1 (0.48) | PELI1BACE1KDM4EPTGS2RAB9A | |
| SCHEMBL15329599 | 0.81 | KDM4E (0.52) | PELI1BACE1KDM4EPTGS2RAB9A | |
| SCHEMBL17309253 | 0.81 | TRIM24 (0.59) | PELI1BACE1KDM4EPTGS2RAB9A | |
| SCHEMBL9305333 | 0.81 | PELI1 (0.62) | PELI1BACE1ALDH1A1HPGDBCL2L1 | |
| SCHEMBL9472211 | 0.80 | PTPN1 (0.53) | PELI1BACE1ALDH1A1HPGDBCL2L1 | |
| SCHEMBL6744610 | 0.79 | PTPN1 (0.49) | PELI1BACE1KDM4EPTGS2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111793091-A | Halogen-free flame-retardant epoxy resin precursor, composition, molding compound product, preparation method and application | 中国科学院宁波材料技术与工程研究所 | 2020-10-20 | — | — | CN | claimed |
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) | 2025-03-20 | — | — | US | disclosed |
| CN-118546109-A | Nitrogen-containing heterocyclic compound and medical application thereof | 哈尔滨三联药业股份有限公司 | 2024-08-27 | — | — | CN | disclosed |
| WO-2023180813-A1 | NARINGENIN OR DERIVATIVES THEREOF FOR IMPROVING SKELETAL MUSCLE ENDURANCE OR FOR TREATING OR PREVENTING MUSCLE ATROPHY OR DYSTROPHY | INSTITUTE OF BIOPHYSICS, CHINESE ACADEMY OF SCIENCES (CN) | 2023-09-28 | — | — | WO | disclosed |
| US-11584742-B2 | Substituted aminothiazoles as inhibitors of nucleases | MASARYKOVA UNIVERZITA (CZ) | 2023-02-21 | — | — | US | disclosed |
| US-11584742-B2 | Substituted aminothiazoles as inhibitors of nucleases | MASARYKOVA UNIVERZITA (CZ) | 2023-02-21 | — | — | US | disclosed |
| WO-2023008577-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | 国立大学法人神戸大学 | 2023-02-02 | — | — | WO | disclosed |
| US-20220002282-A1 | SUBSTITUTED AMINOTHIAZOLES AS INHIBITORS OF NUCLEASES | MASARYKOVA UNIVERZITA (CZ) | 2022-01-06 | — | — | US | disclosed |
| US-20220002282-A1 | SUBSTITUTED AMINOTHIAZOLES AS INHIBITORS OF NUCLEASES | MASARYKOVA UNIVERZITA (CZ) | 2022-01-06 | — | — | US | disclosed |
| EP-3556755-B1 | SUBSTITUTED AMINOTHIAZOLES AS INHIBITORS OF NUCLEASES | UNIV MASARYKOVA (CZ) | 2021-11-17 | — | — | EP | disclosed |
| EP-0450932-A2 | Melt-processable polyester capable of forming an anisotropic melt which exhibits a highly attractive balance between its molding and heat deflection temperatures | HOECHST CELANESE CORPORATION (US) | 1991-10-09 | — | — | EP | disclosed |
| US-5015722-A | Polylactones and polyesters as molding materials | HOECHST CELANESE CORPORATION (US) | 1991-05-14 | — | — | US | disclosed |
| EP-0102160-B1 | ANISOTROPIC MELT PROCESSABLE POLYESTER COMPRISING RELATIVELY LOW CONCENTRATION OF 6-OXY-2-NAPHTHOYL MOIETY | CELANESE CORPORATION (US) | 1986-12-17 | — | — | EP | disclosed |
| US-4522974-A | Melt processable polyester capable of forming an anisotropic melt comprising a relatively low concentration of 6-oxy-2-naphthoyl moiety-4-benzoyl moiety, 1,4-dioxyphenylene moiety, isophthaloyl moiety and terephthaloyl moiety | CELANESE CORPORATION (US) | 1985-06-11 | — | — | US | disclosed |
| US-4473682-A | Melt processable polyester capable of forming an anisotropic melt comprising a relatively low concentration of 6-oxy-2-naphthoyl moiety, 4-oxybenzoyl moiety, 4,4'-dioxybiphenyl moiety, and terephthaloyl moiety | CELANESE CORPORATION (US) | 1984-09-25 | — | — | US | disclosed |
| US-4429100-A | LOW-MELTING, ANISOTROPIC, AROMATIC COPOLYMERS, FIBERS, FILMS | CELANESE CORPORATION (US) | 1984-01-31 | — | — | US | disclosed |
| US-4299756-A | FIBERS, FILMS, AND MOLDING MATERIALS | CELANESE CORPORATION (US) | 1981-11-10 | — | — | US | disclosed |
| US-4299756-A | FIBERS, FILMS, AND MOLDING MATERIALS | CELANESE CORPORATION (US) | 1981-11-10 | — | — | US | disclosed |
| US-4279803-A | Polyester of phenyl-4-hydroxybenzoic acid and 4-hydroxybenzoic acid and/or 6-hydroxy-2-naphthoic acid capable of forming an anisotropic melt | CELANESE CORPORATION (US) | 1981-07-21 | — | — | US | disclosed |
| US-4279803-A | Polyester of phenyl-4-hydroxybenzoic acid and 4-hydroxybenzoic acid and/or 6-hydroxy-2-naphthoic acid capable of forming an anisotropic melt | CELANESE CORPORATION (US) | 1981-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11584742-B2 | Substituted aminothiazoles as inhibitors of nucleases | RNASEH1, DNASE1, FEN1 | PELI1 1682/4885BACE1 564/4885KDM4E 1848/4885 |
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | BRAF, RAF1, NRAS | PELI1 1173/4885BACE1 3328/4885KDM4E 2663/4885 |
| US-20220002282-A1 | SUBSTITUTED AMINOTHIAZOLES AS INHIBITORS OF NUCLEASES | RNASEH1, DNASE1, FEN1 | PELI1 1682/4885BACE1 564/4885KDM4E 1848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.