Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CES1 | P23141 | 6/20 | 0.46 |
| ▸ | CES2 | O00748 | 5/20 | 0.46 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | FABP3 | P05413 | 3/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL674467 | 0.89 | CES1 (0.46) | CA1CES1CES2FFAR3HDAC3 | |
| Methacrylic Acid SCHEMBL6883217 | 0.85 | TSHR (0.39) | CA1CES1CES2FABP3GPR84 | |
| SCHEMBL6072819 | 0.82 | CA1 (0.50) | CA1CES1CES2CA2 | |
| Butyric Acid SCHEMBL11746797 | 0.82 | FFAR3 (0.67) | CA1CES1CES2FFAR3HDAC3 | |
| Fumaric Acid SCHEMBL2940732 | 0.82 | CA1 (0.41) | CA1CES1CES2FABP3 | |
| Fumaric Acid SCHEMBL2940726 | 0.82 | CA1 (0.41) | CA1CES1CES2FABP3 | |
| Thioglycolic Acid SCHEMBL7700486 | 0.82 | CA1 (0.46) | CA1CES1CES2FFAR3HDAC3 | |
| Acrylic Acid SCHEMBL11582286 | 0.80 | TSHR (0.42) | CA1CES1CES2FABP3 | |
| L-Lactic Acid SCHEMBL6072253 | 0.80 | CA1 (0.48) | CA1CES1CES2GPR84CA2 | |
| Trifluoroacetic Acid SCHEMBL6736795 | 0.80 | CES2 (0.45) | CA1CES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8895773-B2 | Manufacture and use of alkyl p-toluates | INVISTA NORTH AMERICA S.A.R.L. (US) | 2014-11-25 | — | — | US | disclosed |
| EP-2291347-A2 | MANUFACTURE AND USE OF ALKYL P-TOLUATES | Invista Technologies S.à.r.l. (CH) | 2011-03-09 | — | — | EP | disclosed |
| US-20090286912-A1 | MANUFACTURE AND USE OF ALKYL p-TOLUATES | INVISTA NORTH AMERICA S.A R.L. (US) | 2009-11-19 | — | — | US | disclosed |
| WO-2009137775-A2 | MANUFACTURE AND USE OF ALKYL P-TOLUATES | INVISTA TECHNOLOGIES S.A R.L. (CH) | 2009-11-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286912-A1 | MANUFACTURE AND USE OF ALKYL p-TOLUATES | EP300, TERT, NAPEPLD | CA1 4636/4885CES1 525/4885CES2 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.