Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORT1 | Q99523 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6746737 | 0.77 | MEN1 (0.46) | NPC1RAB9APOLBMAPTKDM4E | |
| SCHEMBL6751578 | 0.74 | POLB (0.45) | NPC1RAB9ASMN1; SMN2POLBKDM4E | |
| SCHEMBL6680009 | 0.70 | KMT2A (0.49) | POLBKMT2AGAAALDH1A1MEN1 | |
| SCHEMBL12691557 | 0.68 | KDM4E (0.59) | NPC1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL19718181 | 0.67 | P2RX7 (0.44) | NPC1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL11226943 | 0.67 | ALDH1A1 (0.45) | POLBMAPTKDM4EGAAALDH1A1 | |
| SCHEMBL8078737 | 0.67 | POLB (0.38) | NPC1RAB9ASMN1; SMN2POLBMAPT | |
| SCHEMBL12285509 | 0.65 | GAA (0.42) | SMN1; SMN2MAPTKDM4EGAAALDH1A1 | |
| SCHEMBL235710 | 0.64 | KDM4E (0.54) | SORT1KDM4EKMT2AGAACYP1A2 | |
| SCHEMBL30442476 | 0.64 | KDM4E (0.54) | SORT1KDM4EKMT2AGAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1092729-B1 | POLYMERIZATION CATALYST, NOVEL TRANSITION METAL COMPOUND, AND POLYMERIZATION METHOD AND COPOLYMER USING THEM | MITSUI CHEMICALS INC (JP) | 2012-09-26 | — | — | EP | disclosed |
| US-6703459-B1 | ORGANIC TRANSITION METAL COMPLEXES HAVING SPECIFIC STRUCTURE, WHICH CAN FORM COPOLYMERS HAVING LINKAGE FORMED BY MIGRATION OF ACTIVE HYDROGEN OF UNSATURATED MONOMER | MITSUI CHEMICALS, INC. (JP) | 2004-03-09 | — | — | US | disclosed |
| EP-1092729-A1 | POLYMERIZATION CATALYST, NOVEL TRANSITION METAL COMPOUND, AND POLYMERIZATION METHOD AND COPOLYMER USING THEM | Mitsui Chemicals, Inc. (JP) | 2001-04-18 | — | — | EP | disclosed |