Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6751578 | 0.86 | POLB (0.45) | POLBSMN1; SMN2NPC1RAB9ACYP1A2 | |
| SCHEMBL7738430 | 0.82 | GAA (0.55) | POLBGAAPLK1 | |
| SCHEMBL6680009 | 0.80 | KMT2A (0.49) | POLBGAAMEN1KMT2AHTT | |
| SCHEMBL12691557 | 0.78 | KDM4E (0.59) | SMN1; SMN2NPC1RAB9AGAAKDM4E | |
| SCHEMBL7219605 | 0.78 | L3MBTL1 (0.49) | HPGDKMT2ATSHRHTT | |
| SCHEMBL20510174 | 0.77 | ALDH1A1 (0.45) | SMN1; SMN2CYP1A2CYP2C19GAAKDM4E | |
| SCHEMBL11226943 | 0.77 | ALDH1A1 (0.45) | POLBGAAKDM4EHPGDTSHR | |
| SCHEMBL11519985 | 0.77 | KEAP1 (0.51) | POLBRAB9ACYP2C19GAAKDM4E | |
| SCHEMBL16828923 | 0.77 | POLB (0.35) | POLBSMN1; SMN2NPC1RAB9ACYP1A2 | |
| SCHEMBL8861756 | 0.75 | MAPK1 (0.42) | POLBSMN1; SMN2CYP1A2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937730-B1 | Process for preparing silylated carboxylic acid amides | WACKER CHEMIE GMBH (DE) | 2000-08-30 | — | — | EP | disclosed |
| EP-0937730-A2 | Process for preparing silylated carboxylic acid amides | Wacker Siltronic Gesellschaft für Halbleitermaterialien Aktiengesellschaft (DE) | 1999-08-25 | — | — | EP | disclosed |