SCHEMBL674504

SCHEMBL674504

CCOC(=O)CCN1CC1C

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 1/20 0.44
CYP1A2 P05177 1/20 0.42
THRB P10828 5/20 0.42
ALDH1A1 P00352 3/20 0.41
MGAM O43451 1/20 0.41
GAA P10253 1/20 0.41
SI P14410 1/20 0.41
MGAM2 Q2M2H8 1/20 0.41
LMNA P02545 2/20 0.41
POLB P06746 2/20 0.41
TSHR P16473 1/20 0.41
THRA P10827 1/20 0.40
KAT2B Q92831 1/20 0.40
TRPA1 O75762 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL672310 0.86 THRB (0.44) HRH3THRBTHRA
SCHEMBL673561 0.85 THRB (0.48) THRBALDH1A1THRAL3MBTL1
SCHEMBL9327544 0.84 TSHR (0.43) HRH3THRBALDH1A1TSHRTHRA
SCHEMBL16597545 0.83 THRB (0.49) THRBALDH1A1THRAL3MBTL1
SCHEMBL3832651 0.83 HRH3 (0.42) HRH3CYP1A2ALDH1A1LMNAPOLB
SCHEMBL3832656 0.83 HRH3 (0.42) HRH3CYP1A2ALDH1A1LMNAPOLB
SCHEMBL674518 0.82 THRB (0.37) HRH3THRBALDH1A1THRA
SCHEMBL28146 0.82 THRB (0.56) THRBALDH1A1GAATHRAL3MBTL1
SCHEMBL8782251 0.82 THRB (0.35) HRH3THRBALDH1A1LMNATSHR
SCHEMBL13327014 0.81 THRB (0.42) HRH3THRBTHRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3456746-B1 TERMINAL-MODIFIED CONJUGATED DIENE-BASED POLYMER, RUBBER COMPOSITION, AND RUBBER ARTICLE BRIDGESTONE CORP (JP) 2023-04-19 EP disclosed
EP-3851489-A1 MODIFIED MULTI-COMPONENT COPOLYMER, RUBBER COMPOSITION, RESIN COMPOSITION, TIRE AND RESIN PRODUCT BRIDGESTONE CORPORATION (JP) 2021-07-21 EP disclosed
US-10875937-B2 Terminal-modified conjugated diene polymer, rubber composition and rubber article BRIDGESTONE CORPORATION (JP) 2020-12-29 US disclosed
WO-2020054484-A1 MODIFIED MULTI-COMPONENT COPOLYMER, RUBBER COMPOSITION, RESIN COMPOSITION, TIRE AND RESIN PRODUCT 株式会社ブリヂストン 2020-03-19 WO disclosed
US-20190161571-A1 TERMINAL-MODIFIED CONJUGATED DIENE POLYMER, RUBBER COMPOSITION, RUBBER PRODUCT AND METHOD FOR MANUFACTURING TERMINAL-MODIFIED CONJUGATED DIENE POLYMER BRIDGESTONE CORPORATION (JP) 2019-05-30 US disclosed
US-20190153123-A1 TERMINAL-MODIFIED CONJUGATED DIENE POLYMER, RUBBER COMPOSITION AND RUBBER ARTICLE BRIDGESTONE CORPORATION (JP) 2019-05-23 US disclosed
EP-3466985-A1 TERMINALLY MODIFIED CONJUGATED DIENE POLYMER, RUBBER COMPOSITION, RUBBER PRODUCT, AND METHOD FOR PRODUCING TERMINALLY MODIFIED CONJUGATED DIENE POLYMER Bridgestone Corporation (JP) 2019-04-10 EP disclosed
EP-3456746-A1 TERMINAL-MODIFIED CONJUGATED DIENE-BASED POLYMER, RUBBER COMPOSITION, AND RUBBER ARTICLE Bridgestone Corporation (JP) 2019-03-20 EP disclosed
US-10131722-B2 Method for preparing terminal-modified conjugated diene polymer, terminal-modified conjugated diene polymer, rubber composition and tire BRIDGESTONE CORPORATION (JP) 2018-11-20 US disclosed
US-9776045-B2 Carboxylic branched chain-cutting agent for golf ball-covering ionomer resin, golf ball coating composition, and method for manufacturing golf ball QINGDAO FANTOM GOLD CO., LTD. (CN) 2017-10-03 US disclosed
US-20100081759-A1 ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH AZIRIDINE CROSSLINKING AGENTS 3M INNOVATIVE PROPERTIES COMPANY 2010-04-01 US disclosed
US-7652103-B2 Acrylic pressure-sensitive adhesives with aziridine crosslinking agents 3M INNOVATIVE PROPERTIES COMPANY (US) 2010-01-26 US disclosed
US-7652103-B2 Acrylic pressure-sensitive adhesives with aziridine crosslinking agents 3M INNOVATIVE PROPERTIES COMPANY (US) 2010-01-26 US disclosed
US-20090292043-A1 MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES BRIDGESTONE CORPORATION (JP) 2009-11-26 US disclosed
US-20090208740-A1 ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH AZIRIDINE CROSSLINKING AGENTS 3M INNOVATIVE PROPERTIES COMPANY 2009-08-20 US disclosed
US-20090208740-A1 ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH AZIRIDINE CROSSLINKING AGENTS 3M INNOVATIVE PROPERTIES COMPANY 2009-08-20 US disclosed
EP-1975200-A1 RUBBER COMPOSITION CONTAINING MODIFIED POLYBUTADIENE RUBBER AND TIRE Bridgestone Corporation (JP) 2008-10-01 EP disclosed
US-20080177017-A1 Modified Polymer, Rubber Composition, and Tire BRIDGESTONE CORPORATION (JP) 2008-07-24 US disclosed
EP-1873168-A1 MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES Bridgestone Corporation (JP) 2008-01-02 EP disclosed
EP-1834966-A1 MODIFIED POLYMER, RUBBER COMPOSITION, AND TIRE Bridgestone Corporation (JP) 2007-09-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100081759-A1 ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH AZIRIDINE CROSSLINKING AGENTS AAAS, CDH1, PTK2 HRH3 463/4885CYP1A2 3871/4885THRB 4443/4885
US-20090208740-A1 ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH AZIRIDINE CROSSLINKING AGENTS AAAS, CDH1, PTK2 HRH3 463/4885CYP1A2 3871/4885THRB 4443/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.