SCHEMBL6745115

SCHEMBL6745115

C1=CC(C23CC4CC(CC(C4)C2)C3)=CC1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
MEN1 O00255 1/20 0.33
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
GFER P55789 1/20 0.33
KMT2A Q03164 1/20 0.33
USP2 O75604 1/20 0.33
MAPT P10636 1/20 0.33
THRB P10828 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
TSHR P16473 1/20 0.32
EPHX2 P34913 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
GRIN2D O15399 1/20 0.30
GRIN3B O60391 1/20 0.30
GRIN1 Q05586 1/20 0.30
GRIN2A Q12879 1/20 0.30
GRIN2B Q13224 1/20 0.30
GRIN2C Q14957 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15923165 0.79 LMNA (0.34) ALDH1A1LMNAMEN1POLBGAA
SCHEMBL10340245 0.74 MEN1 (0.34) ALDH1A1LMNAMEN1POLBGAA
SCHEMBL3224450 0.67 EPHX2 (0.35) ALDH1A1LMNAMEN1POLBGAA
SCHEMBL21831418 0.65 ALDH1A1 (0.36) ALDH1A1LMNAMEN1POLBGAA
SCHEMBL28299622 0.64 LMNA (0.43) ALDH1A1LMNAMEN1POLBGAA
SCHEMBL3162669 0.64 ALDH1A1 (0.35) ALDH1A1LMNAMEN1POLBGAA
SCHEMBL28141032 0.62 LMNA (0.41) ALDH1A1LMNAMEN1POLBGAA
Hydrochloric Acid SCHEMBL27535208 0.61 ALDH1A1 (0.33) ALDH1A1LMNAMEN1POLBGAA
SCHEMBL2763437 0.61 LMNA (0.77) ALDH1A1LMNAMEN1POLBGAA
SCHEMBL20603895 0.61 LMNA (0.40) ALDH1A1LMNAMEN1POLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6693153-B2 USING COORDINATION CATALYST CALIFORNIA INSTITUTE OF TECHNOLOGY 2004-02-17 US disclosed
US-20030139544-A1 Catalyst system for the polymerization of alkenes to polyolefins ENERGY, UNITED STATES DEPARTMENT OF 2003-07-24 US disclosed
US-6469188-B1 CATALYST SYSTEMS PARTICULARLY USEFUL FOR THE POLYMERIZATION OF POLYPROPYLENE TO GIVE ELASTOMERIC POLYPROPYLENES CALIFORNIA INSTITUTE OF TECHNOLOGY 2002-10-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030139544-A1 Catalyst system for the polymerization of alkenes to polyolefins MSH2, PMS2, SDC4 ALDH1A1 2798/4885LMNA 4272/4885MEN1 1486/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.