Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2801373 | 0.86 | TRPV4 (0.52) | TRPV4CYP11B1CYP11B2PDCD1CD274 | |
| SCHEMBL2800490 | 0.86 | TRPV4 (0.52) | TRPV4EGFR | |
| SCHEMBL28341814 | 0.77 | TRPV4 (0.44) | TRPV4CYP11B1CYP11B2PDCD1CD274 | |
| SCHEMBL7562408 | 0.75 | CYP11B2 (0.47) | TRPV4CYP11B1CYP11B2 | |
| SCHEMBL2726074 | 0.74 | TRPV4 (0.48) | TRPV4 | |
| SCHEMBL31371999 | 0.74 | TRPV4 (0.39) | TRPV4CYP11B1CYP11B2PDCD1CD274 | |
| SCHEMBL12465035 | 0.74 | GRM5 (0.35) | PDCD1CD274EGFR | |
| SCHEMBL15157689 | 0.73 | TRPV4 (0.40) | TRPV4 | |
| SCHEMBL3839778 | 0.71 | ACHE (0.42) | EGFR | |
| SCHEMBL13243340 | 0.71 | ACHE (0.42) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1423362-A1 | NEW MANDELIC ACID DERIVATIVES AND THEIR USE AS THROMBIN INHIBITORS | AstraZeneca AB (SE) | 2004-06-02 | — | — | EP | disclosed |
| WO-2003018551-A1 | NEW MANDELIC ACID DERIVATIVES AND THEIR USE AS THROMBIN INHIBITORS | ASTRAZENECA AB (SE) | 2003-03-06 | — | — | WO | disclosed |